Results 181 to 190 of about 365,969 (214)

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Advancing Evidence-Based Medicine for Population, Intervention, Comparison, and Outcome Element Recognition and Extraction in Medical Literature: Large Language Model Approach. [PDF]

J Med Internet Res
Hao Z, Duan Y, Wang Y.
europepmc   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Review of Welding Technologies for Electronic Precision Equipment: Status, Limitations, and Prospects. [PDF]

Materials (Basel)
Cai H, Wang R, Feng X, Cao H, Wang T, Yu H, Su M.   +6 more
europepmc   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Engineered MSC-exosomes as CRISPR-Cas9 delivery vectors for precision immunotherapy. [PDF]

Front Bioeng Biotechnol
Guo D, Zhang W, Dou W, Yang Y, Sun B, Qiu M, Wang K, Zhai J, Feng S.   +8 more
europepmc   +1 more source

Temporal Divergence of True and False Alarms in Pediatric Nocturnal Seizure Monitoring

Annals of Clinical and Translational Neurology, EarlyView.
The early‐morning surge in false seizure alarms supports exploring time‐ or state‐dependent detection thresholds to reduce false detections. ABSTRACT Seizure detection devices can improve the safety of children with epilepsy, yet high false alarms limit their clinical applicability.
Mohammad Shahbakhti, Anemoon T. Bosch, Job van der Palen, Franciscus S. Leijten, Johannes P. van Dijk, Richard H. C. Lazeron, Roland D. Thijs   +6 more
wiley   +1 more source

Design and performance evaluation of a solar powered remote controlled robot for precision seed planting. [PDF]

Sci Rep
Aboharg S, Abdelfattah EK, Abdelmotaleb I, Eldesoukey A, Omara ZM, Sharaby N.   +5 more
europepmc   +1 more source

Engineering Nutritional Profiles in Edible Insects Through Diet-Microbiome Interactions: Mechanisms, Applications and Future Directions. [PDF]

Insects
Ezzaitouni M, Chelh TC, Belarbi EH, Guil-Guerrero JL.   +3 more
europepmc   +1 more source

Precision Microalgae: A New Conceptual Framework for Bioengineering Applications. [PDF]

Bioengineering (Basel)
Dutra DA, Machado RLS, Deprá MC, Schneider AT, Machado EF, Fagundes MB, Zepka LQ, Jacob-Lopes E.   +7 more
europepmc   +1 more source