Results 171 to 180 of about 4,130,659 (297)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Unlocking MENA's potential in rare-disease precision medicine. [PDF]

Orphanet J Rare Dis
Tabarki B, Hundallah K, Alfadhel M.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Editorial: Precision Medicine in Neonates

Frontiers in Pediatrics, 2021
Karel Allegaert, Karel Allegaert, Karel Allegaert, Sinno Simons   +3 more
doaj   +1 more source

Diagnostic Lag in Precision Medicine. [PDF]

Clin Pharmacol Ther
Heneberg P.
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A decade of Genome Medicine: toward precision medicine

Genome Medicine, 2019
Rabia Begum
doaj   +1 more source

Population proteomics for equitable precision medicine. [PDF]

EMBO Mol Med
Yu X, Yang J, Yu B, Yu JT.
europepmc   +1 more source

Ultra-precision medicine [PDF]

Nature Biotechnology, 2021
openaire   +2 more sources

Reporting guidelines for precision medicine research of clinical relevance : the BePRECISE checklist

Precision medicine should aspire to reduce error and improve accuracy in medical and health recommendations by comparison with contemporary practice, while maintaining safety and cost-effectiveness.
Rich, Stephen S, Lim, Siew S, Gomez, Maria F., Dennis, JM, Boyle, Jacqueline, Merino, J, Semnani-Azad, Zhila, Hivert, M-F, Sattar, N, Trenell, Michael I,, Boyle, Jacqueline,, Collin, C, Franks, Paul W,, Morieri, Mario L, Semnani-Azad, Z, Franks, Paul W., Sattar, Naveed,, Collin, Christian, Sargent, JL, Trenell, Michael I., Ahmad, Abrar,, Tobias, DK, Ramsay, M, Sanyal, AJ, Rich, SS, Lim, Siew S,, Ahmad, Abrar, Lim, Siew S., Trenell, MI, Hivert, Marie-France,, Ng, AH, Gomez, MF, Loos, RJF, Morrison, M, Dennis, John M, Gomez, Maria F, Sargent, Jennifer L, Langenberg, C, Ng, Ashley H, Trenell, Michael I, Lund University., Ahmad, A, Fitipaldi, Hugo, Morrison, Melinda,, Merino, Jordi,, Langenberg, Claudia,, Sargent, Jennifer L., Collin, Christian,, Hivert, Marie-France, Semnani-Azad, Zhila,, Ng, Ashley H., Loos, Ruth J F, Ng, Ashley H,, Morrison, Melinda, Langenberg, Claudia, Morieri, Mario L., Fitipaldi, Hugo,, Morieri, Mario L,, Franks, Paul W, Sanyal, Arun J,, Lim, SS, Sanyal, Arun J., Tobias, Deirdre K,, Tobias, Deirdre K., Ramsay, Michele, Tobias, Deirdre K, Loos, Ruth J F,, Morieri, ML, Sattar, Naveed, Hivert, Marie France, Boyle, J, Ramsay, Michele,, Franks, PW, Rich, Stephen S., Dennis, John M,, Dennis, John M., Rich, Stephen S,, Loos, Ruth J.F., Merino, Jordi, Fitipaldi, H, Sanyal, Arun J, Gomez, Maria F,, Sargent, Jennifer L,   +82 more
core   +1 more source