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Clinical proteomics for precision medicine: the bladder cancer case [PDF]
, 2017 Precision medicine can improve patient management by guiding therapeutic decision based on molecular characteristics. The concept has been extensively addressed through the application of –omics based approaches.
Frantzi, Maria +4 more
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The new medical model: a renewed challenge for biomedicine [PDF]
, 2017 Over the past 25 years, several new “medicines” have come screeching onto health care’s various platforms, including narrative medicine, personalized medicine, precision medicine and person-centred medicine.
Fuller, Jonathan
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Genetics update: monogenetics, polygene disorders and the quest for modifying genes [PDF]
, 2018 The genetic channelopathies are a broad collection of diseases. Many ion channel genes demonstrate wide phenotypic pleiotropy, but nonetheless concerted efforts have been made to characterise genotype-phenotype relationships.
Symonds, Joseph D., Zuberi, Sameer M.
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Precision medicine informatics [PDF]
Journal of the American Medical Informatics Association, 2016 This special issue on precision medicine informatics flowed from the AMIA 2015 Translational Bioinformatics Summit theme of “Accelerating Precision Medicine”1 and President Obama’s 2015 State of the Union call “to give all of us access to the personalized information we need to keep ourselves and our families healthier.”2 The goal is to focus on the ...
Frey, Lewis J +2 more
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Precision Medicine in Lung Cancer
European Medical Journal Oncology, 2020 Lung cancer has a devastating global impact, with diagnosis of more than 2 million new cases annually, and poor long-term survival. Recently, the landscape of lung cancer diagnosis, staging, and treatment has changed profoundly, with further developments
Esha Joshi
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Snapshot: Trial Types in Precision Medicine. [PDF]
, 2020 Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but
Bergan, Raymond +5 more
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Developing precision stroke imaging. [PDF]
, 2014 Stroke experts stand at the cusp of a unique opportunity to advance the care of patients with cerebrovascular disorders across the globe through improved imaging approaches.
Feldmann, Edward, Liebeskind, David S
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Management of clinical precision medicine
Clinical and Translational Discovery, 2021 Precision medicine is an emerging approach for patient treatment as it allows clinicians to select therapies based on the genetic understanding of the disease.
Hao Chen +4 more
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Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome. [PDF]
, 2017 In the 50 years since acute respiratory distress syndrome (ARDS) was first described, substantial progress has been made in identifying the risk factors for and the pathogenic contributors to the syndrome and in characterising the protein expression ...
Calfee, Carolyn S, Meyer, Nuala J
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Engineering Precision Medicine [PDF]
Advanced Science, 2018 AbstractAdvances in genomic sequencing and bioinformatics have led to the prospect of precision medicine where therapeutics can be advised by the genetic background of individuals. For example, mapping cancer genomics has revealed numerous genes that affect the therapeutic outcome of a drug.
Wujin Sun +5 more
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