Results 51 to 60 of about 164,371 (301)
Precision Medicine in Oncology and Cancer Therapeutics
, 2022 The definition of precision medicine changed in the twenty-first century several times due to advances in molecular biology, genomics, biotechnology, and data science.
Brand, Angela +4 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Precision oncology in liver cancer [PDF]
Annals of Translational Medicine, 2018 With the widespread adoption of molecular profiling in clinical oncology practice, many physicians are faced with making therapeutic decisions based upon isolated genomic alterations. For example, epidermal growth factor receptor tyrosine kinase inhibitors (TKIs) are effective in EGFR-mutant non-small cell lung cancers (NSCLC) while anti-EGFR ...
Kevin M, Sullivan +4 more
openaire +2 more sources
Communicating About Precision Oncology
, 2017 Communication in oncology has always been challenging. The new era of precision medicine complicates communication even further as a result of our increasing reliance on genomic data and the varying psychological responses to genomic-based treatments ...
Daniel C. McFarland +3 more
core +1 more source
Critical Issues in Head and Neck Oncology [PDF]
, 2021 This open access book discusses the most current issues in head and neck cancer with a focus on current trends such as biomarkers, precision medicine and immunotherapy.
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Charting a Course for Precision Oncology
Clinical Pharmacology & Therapeutics, 2017 The fields of science have undergone dramatic reorganizations as they have come to terms with the realities of the growing complexities of their problem set, the costs, and the breadth of skills needed to make major progress. A field such as particle physics transformed from principal investigator‐driven research supported by an electron synchrotron in
D, Kusnezov, J, Paragas
openaire +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
iBiopsy® for Precision Medicine
European Medical Journal, 2018 A high-throughput artificial intelligence-powered image-based phenotyping platform, iBiopsy® (Median Technologies, Valbonne, France), which aims to improve precision medicine, is discussed in the presented review.
Johan Brag +4 more
doaj
Pneumonitis After Precision Oncology Therapies: A Concise Review [PDF]
Journal of Immunotherapy and Precision Oncology, 2018 With greater understanding of the molecular biology of cancer, precision oncology therapies are becoming increasingly prevalent. Adverse events associated with these therapies may cause significant harm to patients if not promptly recognized and treated.
Akash Jain +2 more
doaj +1 more source