Editorial: Advances of synchrotron radiation-based X-ray imaging in biomedical research
Elena Longo +9 more
doaj +1 more source
From bench to bedside: relevant animal models across the migraine attack phases. [PDF]
Krivoshein G +8 more
europepmc +1 more source
A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret +6 more
wiley +1 more source
Dual-target CAR-T cell therapy: latest updates from the 2025 ASH annual meeting. [PDF]
Feng S, Kong R, Xiao L, Zhou X.
europepmc +1 more source
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach +4 more
wiley +1 more source
Preclinical and Virtual Models of Mucosal Melanoma: Bridging Translational Gaps in a Rare and Lethal Cancer. [PDF]
Jin X, Zhang Y, Zhu Y, Zhang Z, Shi C.
europepmc +1 more source
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
Editorial: Insights into gastrointestinal cancer metastasis from preclinical models. [PDF]
Costa B, Schledwitz A, Raufman JP.
europepmc +1 more source
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Bridging the Gap: Evaluating the Effectiveness of Haptic Simulators Compared to Traditional Methods in Preclinical Dental Education. [PDF]
Lopes PC +6 more
europepmc +1 more source

