Results 201 to 210 of about 6,451,122 (364)

Biomimetic Glycosaminoglycan‐Analog Hydrogel for Improved Embolization of Aneurysms: Environment‐Selective Swelling

Advanced Healthcare Materials, EarlyView.
Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan, Iris Bonshtein, Maria Khoury, Yevgeniy Kreinin, Dmitry Korneyev, Tirosh Mekler, Sumaya Kaiyal, Iris Sonia Weitz, Netanel Korin   +8 more
wiley   +1 more source

Preclinical evaluation of a bispecific low‐molecular heterodimer targeting both PSMA and GRPR for improved PET imaging and therapy of prostate cancer [PDF]

, 2014
Matthias Eder, Martin Schäfer, Ulrike Bauder‐Wüst, Uwe Haberkorn, Michael Eisenhut, Klaus Kopka   +5 more
openalex   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Disruption of normal brain distribution of [18F]Nifene to α4β2* nicotinic acetylcholinergic receptors in old B6129SF2/J mice and transgenic 3xTg-AD mice model of Alzheimer's disease: In Vivo PET/CT imaging studies

NeuroImage
The 3xTg-AD transgenic mouse model develops Aβ plaque and tau pathology and is purported to closely resemble pathological development in the human Alzheimer's disease (AD) brain.
Christopher Liang, Atsumi A. Okamoto, Fariha Karim, Shimako Kawauchi, Lusine Melkonyan, Tram B. Danh, Jogeshwar Mukherjee   +6 more
doaj  

Identifying preclinical imaging markers of radiation side effects: An animal brain tumor model to correlate radiation-induced imaging changes, neurogenesis and cognitive impairment

, 2010

openalex   +1 more source

Non‐Surgical, In‐Stent Membrane Bioelectronics for Long‐Term Intracranial Pressure Monitoring

Advanced Healthcare Materials, EarlyView.
This image shows a sequence of long‐term intracranial pressure monitoring using non‐surgical, in‐stent membrane bioelectronics. Abstract Traditional intracranial pressure (ICP) monitoring methods, using intraventricular catheters, face significant limitations, including high invasiveness, discrete data, calibration complexities, and drift issues, which
Jimin Lee, Allison Bateman, Mi Hyeon Kim, Bruno Rigo, Hodam Kim, Jaeho Lee, Yun Hyeok Choi, Robert Herbert, Deok Hee Lee, Woon‐Hong Yeo   +9 more
wiley   +1 more source

Thrombus Imaging Using 3D Printed Middle Cerebral Artery Model and Preclinical Imaging Techniques: Application to Thrombus Targeting and Thrombolytic Studies. [PDF]

Pharmaceutics, 2020
Vítečková Wünschová A, Novobilský A, Hložková J, Scheer P, Petroková H, Jiřík R, Kulich P, Bartheldyová E, Hubatka F, Jonas V, Mikulík R, Malý P, Turánek J, Mašek J.   +13 more
europepmc   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Visualization, imaging and new preclinical diagnostics in radiation oncology [PDF]

, 2014
Clemens C. Cyran, Philipp M. Paprottka, Michel Eisenblätter, Dirk‐André Clevert, Carsten Rist, Konstantin Nikolaou, Kirsten Lauber, Frederik Wenz, Daniel Hausmann, Maximilian F. Reiser, Claus Belka, Maximilian Niyazi   +11 more
openalex   +1 more source