Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles
Advanced Functional Materials, EarlyView.Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati +2 more
wiley +1 more source
Thrombus Imaging Using 3D Printed Middle Cerebral Artery Model and Preclinical Imaging Techniques: Application to Thrombus Targeting and Thrombolytic Studies. [PDF]
Pharmaceutics, 2020 Vítečková Wünschová A +13 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
Exploring the Feasibility of Zero-Shot Super-Resolution in Preclinical Imaging. [PDF]
Med Image Comput Comput Assist IntervGharib OAM +4 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak +6 more
wiley +1 more source
In ovo model with emu eggs as novel alternative to animal testing in preclinical imaging research. [PDF]
EJNMMI ResPerkas O +7 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of cancer studies and drug screening. [PDF]
F1000ResSchulze J +9 more
europepmc +1 more source
Multimodal imaging guided preclinical trials of vascular targeting in prostate cancer
, 2015 James Kalmuk +4 more
openalex +2 more sources
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Advanced Healthcare Materials, EarlyView.Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source