Results 301 to 310 of about 6,725,081 (364)

3D Bioprinted Human Synovium‐Cartilage Models Mimic Rheumatoid Arthritis Microenvironment and Recapitulate In Vivo Therapeutic Responses

Advanced Materials, EarlyView.
This study presents human in vitro rheumatoid arthritis models using chondrocytes recellularized type II collagen scaffold and 3D‐bioprinted Gelatin‐Matrigel hydrogels with fibroblast‐like synoviocytes, pro‐inflammatory macrophages, and protective barrier macrophages, closely recapitulating key rheumatoid arthritis pathological features.
Huiqun Zhou, Zhen Zhang, Yulei Mu, Liang Ma, Xu Hu, Bangheng Liu, Dong‐An Wang   +6 more
wiley   +1 more source

Performance evaluation of the ACTIVE 7 MAX benchtop preclinical PET scanner in accordance with the NEMA NU 4-2008 standard. [PDF]

EJNMMI Phys
Wang H, Wang K, Yuan Z, Li C, Liao R, Hou Y, Hua J, Tang Y, Ruan Q, Han D, Jiang J.   +10 more
europepmc   +1 more source

2D/3D CMR tissue tracking versus CMR tagging in the assessment of spontaneous T2DM rhesus monkeys with isolated diastolic dysfunction [PDF]

, 2018
et al,, Zheng, Jie
core   +1 more source

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Near-Infrared Fluorescence Imaging With Indocyanine Green for Intraoperative Nerve Root Visualization in Spinal Surgery: From Preclinical Studies to a Pilot Randomized Controlled Trial. [PDF]

Global Spine J
Huang H, Chen Z, Wu S, Wang L, Zhu X, Xiao L, Deng Z, Wei R, Gu M, Cai L, Lei J, Xie Y.   +11 more
europepmc   +1 more source

Developmentand Preclinical Characterization of [¹⁸F]H3-2406 and [¹⁸F]H3-2407 for Positron EmissionTomography Imaging of the Histamine Subtype‑3 Receptor

Zhendong Song (9731871), Yinlong Li (1884139), Kenneth Dahl (4782936), Zhenkun Sun (1286034), Jiahui Chen (1818361), Xin Zhou (54275), Yabiao Gao (9991754), Jian Rong (598108), Chunyu Zhao (1977382), Katherine Yuan (21725559), Ahmad F. Chaudhary (19923541), Jimmy S. Patel (4453471), Thomas L. Collier (3637486), Chongzhao Ran (222663), Kim S. Muehlfenzl (21725562), Achi Haider (20428250), Charles S. Elmore (2004724), Magnus Schou (1408873), Steven H. Liang (1341546)   +18 more
openalex   +1 more source

Autonomous Hydrogel Actuators Programmed by Endogenous Biochemical Logic for Dual‐Stage Morphing and Drug Release

Advanced Materials, EarlyView.
A 3D‐printed BSA–PEGDA bilayer actuator performs biochemical logic, bending autonomously in acid and releasing its drug payload only when both acid and pepsin are present. This dual‐stage, enzyme‐gated mechanism enables autonomous catch‐and‐release motion and controlled gastric drug delivery, representing a programmable soft material powered by ...
Yuchen Liu, Harischandra Potthuri, Alejandro Sosnik, Luai R. Khoury   +3 more
wiley   +1 more source

Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain

Advanced Materials, EarlyView.
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha, Bilguun Nurzed, Mostafa Berangi, Andre Kuehne, Helmar Waiczies, Igor Fabian Tellez Ceja, Xiang Hu, Thomas Gladytz, Lisa Krenz, Dave Huebler, Beate Endemann, Claudia Brockmann, Ebba Beller, Oliver Stachs, Thoralf Niendorf   +14 more
wiley   +1 more source

Ultrasound imaging in orthotopic hepatocellular carcinoma models: Promise, practicality, and points for refinement. [PDF]

World J Hepatol
Ghosh D, Kumar A.
europepmc   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source