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Preclinical Imaging for Laboratory Rodents
Essentials of Laboratory Animal Science: Principles and Practices, 2021Laboratory animals play an important role in biomedical research and act as a backbone of new drug research and development. Biomedical research is primarily dependent on laboratory rodents. There is a steady shift of therapeutic strategies for diseases from physiological to cellular and presently molecular targets.
P. Chaudhari
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Cardiovascular preclinical imaging.
The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2017Non-invasive imaging in the form of single-photon emission-computed tomography (SPECT), positron-emission tomography (PET), computed tomography (CT), echocardiography or magnetic resonance imaging (MRI) is a very useful tool for cardiovascular research as it allows assessment of biological processes in vivo.
S. Nekolla +3 more
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Preclinical imaging anesthesia in rodents.
The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2017Despite the outstanding progress achieved by preclinical imaging science, laboratory animal anesthesia remains quite stationary. Ninety percent of preclinical imaging studies are carried on small rodents (mice and rats) anesthetized by outdated injectable and/or inhalation agents.
G. Vesce, F. Micieli, L. Chiavaccini
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Is There a Role of Artificial Intelligence in Preclinical Imaging?
Seminars in nuclear medicine, 2023This review provides an overview of the current opportunities for integrating artificial intelligence methods into the field of preclinical imaging research in nuclear medicine.
Alina T. Küper +9 more
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Preclinical Imaging of Cardiovascular Disesase
Seminars in Nuclear Medicine, 2023Noninvasive imaging techniques, such as SPECT, PET, CT, echocardiography, or MRI, have become essential in cardiovascular research. They allow for the evaluation of biological processes in vivo without the need for invasive procedures. Nuclear imaging methods, such as SPECT and PET, offer numerous advantages, including high sensitivity, reliable ...
Stephan G. Nekolla +2 more
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Preclinical Multimodality Imaging in Vivo
PET Clinics, 2008Multimodality small-animal molecular imaging has become increasingly important as transgenic and knockout mice are produced to model human diseases. With the ever-increasing number and importance of human disease models, particularly in rodents (mice and rats), the ability of high-resolution multimodality molecular imaging instrumentation to contribute
Stout, David B., Zaidi, Habib
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Preclinical Imaging: Experimental Example
, 2016Dedicated small animal imaging represents an innovative and fast-growing tool that has demonstrated promising results in the field of preclinical research. New technologies constitute a key factor in the success and timelines of research because of the possibility of conducting longitudinal studies on the same animal.
D. Berritto +4 more
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Preclinical Imaging in Targeted Cancer Therapies
Seminars in Nuclear Medicine, 2019Preclinical imaging with radiolabeled probes can provide noninvasive tools to test the efficacy of targeted agents in tumors harboring specific genetic alterations and to identify imaging parameters that can be used as pharmacodynamics markers in cancer patients. The present review will primarily focus on preclinical imaging studies that can accelerate
Iommelli Francesca +4 more
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Preclinical Imaging in Bone Tissue Engineering
Tissue Engineering Part B: Reviews, 2014Since X-rays were discovered, in 1895, and since the first radiological image of a hand, bone tissue has been the subject of detailed medical imaging. However, advances in bone engineering, including the increased complexity of implant scaffolds, currently also underline the limits of X-ray imaging.
Ventura, M. +8 more
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Technologies: preclinical imaging for drug development
Drug Discovery Today: Technologies, 2013Preclinical imaging with magnetic resonance imaging (MRI), computerised tomography (CT), ultrasound (US), positron emission tomography (PET) or single-photon emission computed tomography (SPECT) enable non-invasive measures of tissue structure, function or metabolism in vivo.
Paul M, Matthews +6 more
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