Results 41 to 50 of about 2,866 (282)
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Symbolic Violence in Tengiz Abuladze’s 'Repentance'
Linguaculture, 2011 This paper examines three dimensions of symbolic violence within a totalitarian state (the elimination of individuality, the preclusion of a sense of community, and the disappearance of the boundary between oppressor and oppressed), which can be ...
Ilinca-Miruna Diaconu
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Boletín Mexicano de Derecho Comparado, 2020 La justicia de familia en Chile experimentó un cambio cardinal en 2005, al pasar de un procedimiento escrito a uno oral y desformalizado. Sin embargo, a pesar de que han transcurrido 14 años, dentro de los que se han experimentado constantes ...
Francesco Carretta Muñoz
doaj +1 more source
Matching preclusion for k-ary n-cubes
, 2010 The (conditional) matching preclusion number of a graph is the minimum number of edges whose deletion leaves a resulting graph (with no isolated vertices) that has neither perfect matchings nor almost perfect matchings.
Jing Li +7 more
core +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Ius et Praxis, 2009 El artículo tiene por objeto llenar cierto vacío en la literatura nacional sobre la preclusion, proponiendo, además, un enfoque jurídico valorativo para la comprensión de las formas preclusivas.
Eduardo Gandulfo R
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells
Stem Cells International, 2021 Although human induced pluripotent stem cells (iPSCs) can serve as a universal cell source for regenerative medicine, the use of iPSCs in clinical applications is limited by prohibitive costs and prolonged generation time.
Yoo-Wook Kwon +10 more
doaj +1 more source