Results 41 to 50 of about 1,561 (213)

La acusación en Colombia

open access: yesDerecho Penal y Criminología, 2011
Para abordar los problemas de la acusación se acude a otras figuras que incluye el derecho procesal colombiano. Afirmamos que no existe una regulación específica que se relacione con el retiro de la acusación y, por tanto, debemos acudir a los mecanismos
Ángela María Buitrago Ruiz
doaj   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Preclusion of radiation-mediated hematological and biochemical variations by root extract of Tinospora cordifolia (an indian medicinal plant) [PDF]

open access: yesNuclear Technology and Radiation Protection, 2013
The present study deals with the radiomodulatory influence of Tinospora cordifolia (Amrita) root extract on the peripheral blood of Swiss albino mice after 5.0 Gy gamma irradiation in the presence (experimental) or absence (control) of Tinospora
Sharma Priyanka, Goyal Pradeep K.
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Procedimientos tributarios: cuestiones polémicas

open access: yesRevista Vasca de Administración Pública, 2014
The procedural facets are becoming increasingly important when claiming the liquidations carried out by the tax office. Some of these facets deal with the delay in the tax inspector procedura, tax infringements and preclusión.
Aitor Orena Domínguez
doaj   +1 more source

La négation phrastique et les indéfinis négatifs en créole vincentien

open access: yesÉtudes Créoles, 2018
In this study we examine the co-occurrence or preclusion of negative words (n-words) with sentential negation in Vincentian Creole which has drawn much of its lexicon from English.
Paula Prescod
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

智慧財產案例有效性判斷爭議 ― 以美國法「爭點排除」為主 Disputed Issues in Deciding the Validity of Intellectual Property Right ― A Focus on Issue Preclusion [PDF]

open access: yesKējì Fǎxué Pínglùn, 2009
我國智慧財產訴訟新制結合民事、刑事、行政訴訟三種訴訟程序,法院就當事人主張或抗辯智慧財產權有應撤銷、廢止之原因者,對其主張或抗辯有無理由自為判斷之結果,引起民事、刑事、行政訴訟關於智慧財產有效性判斷歧異之問題。 智慧財產權有效性判斷歧異爭議或可藉由擴大爭點效之效力,以避免裁判歧異,美國法爭點排除(issue preclusion)相關理論值得加以參考。依智慧財產案件審理法第33條規定,並未明文限制當事人於前案訴訟程序中,就同一撤銷或廢止理由得提出而未提出智慧財權撤銷、廢止之新證據,不得另案主張 ...
陳國成 Kuo-Cheng Chen
doaj  

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