Teratoid Hepatoblastoma: Clinicopathologic Features and Outcomes
Pediatric Blood &Cancer, Volume 72, Issue 10, October 2025.ABSTRACT Background Teratoid hepatoblastoma (HB) is a rare histologic subtype of the most common pediatric liver cancer. Understanding of the clinicopathologic features and outcomes of patients with this disease is currently limited. Methods Multi‐institution, retrospective chart review was conducted to compare 20 children with teratoid HB to 129 ...
Brian T. Hickner +8 more
wiley +1 more source
Weight Gain in Infancy and Childhood Were Associated With Pubertal Development in Boys and Girls
Acta Paediatrica, Volume 114, Issue 10, Page 2612-2618, October 2025.ABSTRACT Aim As earlier puberty has been associated with higher later metabolic risk, we studied how weight gain in infancy and childhood is associated with pubertal timing and duration in healthy children. Method Leveraging the longitudinal data from the Special Turku Coronary Risk Factor Intervention Project study, we used linear regression analyses ...
Saga Rebecca Nummela +5 more
wiley +1 more source
Polyostotic Fibrous Dysplasia With and Without McCune-Albright Syndrome-Clinical Features in a Nordic Pediatric Cohort [PDF]
, 2018 Objective: Fibrous dysplasia (FD) presents as skeletal lesions in which normal bone is replaced by abnormal fibrous tissue due to mosaic GNAS mutation.
Bjornsdottir, Sigridur +4 more
core +1 more source
Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women
Clinical Endocrinology, Volume 103, Issue 4, Page 540-566, October 2025.ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan +14 more
wiley +1 more source
Central precocious puberty and gonadotropin releasing hormone agonist treatment [PDF]
, 1996 In order to understand the processes occurring during precocious puberty, one needs to specify what is currently known about normal pubertal development.
Oostdijk, W. (Wilma)
core
Precocious Puberty: Etiology and Current Treatment [PDF]
, 2023 Precocious puberty also known as premature puberty is an abnormal pubertal development that can affect a child's growth and development. The clinical manifestations of precocious puberty are generally diverse and based on etiology are classified into ...
Ajmala, Indana Eva +8 more
core +1 more source
Psychosocial dimensions of early-onset puberty and its treatment [PDF]
, 2016 Medical journals and popular media present early-onset puberty as a source of substantial parental, medical, and social concern—even a crisis. An article written by parents and a related editorial commentary in Archives of Disease in Childhood,1 for ...
Roberts, Celia Mary
core +1 more source
Present and Future of Central Disorders of Hypersomnolence
Journal of Sleep Research, Volume 34, Issue 5, October 2025.ABSTRACT Central disorders of hypersomnolence (CDH) are rare neurological conditions lumped by excessive daytime sleepiness (EDS) as primary complaint mostly arising at young age, including narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), idiopathic hypersomnia (IH), and Kleine‐Levin syndrome (KLS). Advances in clinical and translational research have
Francesco Biscarini +4 more
wiley +1 more source
MKRN3 Mutations in Central Precocious Puberty: A Systematic Review and Meta-Analysis
Journal of the Endocrine Society, 2019 MKRN3 mutations represent the most common genetic cause of central precocious puberty (CPP) but associations between genotype and clinical features have not been extensively explored.
L. Valadares +10 more
semanticscholar +1 more source
Novas perspectivas no diagnóstico do hipogonadismo pediátrico masculino: a importância do AMH como marcador de células de Sertoli [PDF]
, 2011 Sertoli cells are the most active cell population in the testis during infancy and childhood. In these periods of life, hypogonadism can only be evidenced without stimulation tests, if Sertoli cell function is assessed.
Grinspon, Romina, Rey, Rodolfo Alberto
core +2 more sources