Results 101 to 110 of about 30,684 (278)
Environmental chemical exposures and breast cancer [PDF]
, 2016 As a hormone-sensitive condition with no single identifiable cause, breast cancer is a major health problem. It is characterized by a wide range of contributing factors and exposures occurring in different combinations and strengths across a lifetime ...
Plant, J, Stanley, E, Voulvoulis, N
core +2 more sources
European Journal of Neurology, Volume 33, Issue 1, January 2026.Clinical exome sequencing (CES) was performed on 108 Spanish patients with suspected hereditary spastic paraparesis (HSP), using a virtual 129‐gene panel and HPO‐based variant filtering. A molecular diagnosis was achieved in 53% of cases, with 21 causative genes identified (8 novel variants), SPAST (AD) and SPG7 (AR) being the most frequent genetic ...
Lidón Carretero‐Vilarroig +8 more
wiley +1 more source
Case Reports in Genetics, 2013 We report a girl with a de novo distal deletion of 9p affected by idiopathic central precocious puberty and intellectual disability. Genome-wide array-CGH revealed a terminal deletion of about 11 Mb, allowing to define her karyotype as 46; XX, del(9)(p23-
Mariangela Cisternino +10 more
doaj +1 more source
Combined diagnostic value of insulin-like growth factor-1, insulin-like growth factor binding protein-3, and baseline luteinizing hormone levels for central precocious puberty in girls [PDF]
, 2022 Lixue Ouyang, Fan Yang
openalex +1 more source
Genetic Regulation of Puberty Timing in Humans. [PDF]
, 2015 Understanding the regulation of puberty timing has relevance to developmental and human biology and to the pathogenesis of various diseases. Recent large-scale genome-wide association studies on puberty timing and adult height, body mass index (BMI) and ...
Day, Felix R, Ong, Ken K, Perry, John RB
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A New Program for Determining Abnormal Growth Curves in School Health Checkups
Journal of School Health, Volume 96, Issue 1, January 2026.ABSTRACT Background In Japan, school health examinations frequently utilize growth curves. This study aimed to develop and validate a custom‐designed program that enables the rapid and accurate detection of growth abnormalities in children and adolescents. Methods We created a novel screening tool named the Growth Assessment Program for Schools (GAPS),
Keisuke Wada +5 more
wiley +1 more source
Changes in body mass index in boys with central precocious puberty over 2 years of gonadotropin-releasing hormone agonist therapy [PDF]
, 2020 Kyung In Lim +2 more
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Homeostasis as the Mechanism of Evolution. [PDF]
, 2015 Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic ...
Torday, John S
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Obesity Reviews, Volume 27, Issue 1, Page 1-21, January 2026.ABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine disorder with a complex pathogenesis that includes disordered follicle development, hypothalamic–pituitary–ovarian (HPO) axis dysfunction, hyperandrogenemia, and insulin resistance. The risk of complications during pregnancy, such as gestational diabetes mellitus (GDM) and preeclampsia (PE)
Shaohua Zhang +5 more
wiley +1 more source
Scientific ReportsThe prevalence of obesity-associated precocious puberty is gradually increasing, but the relationship between gut flora and obesity-associated precocious puberty remains unclear.We analysed the gut flora characteristics of a clinical sample of 30 girls ...
Ying Qian +4 more
doaj +1 more source