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Precocious Puberty in Boys

New England Journal of Medicine, 1999
Normal puberty starts when pulsatile release of gonadotropin-releasing hormone (GnRH) from the hypothalamus begins. This triggers the release of luteinizing hormone and follicle-stimulating hormone from the pituitary. In both sexes, these pituitary hormones then activate gonadal function.
Brunner, H.G., Otten, B.J.
openaire   +3 more sources

Growth in precocious puberty

The Indian Journal of Pediatrics, 2006
Growth in precocious puberty is a subject of concern to families and clinicians alike. The definition of precocious puberty and the role of obesity in the age of onset have also been areas of debate since the Lawson Wilkins Society recommended a lowering of the age of onset of precocious puberty in US girls.
Garry L. Warne   +2 more
openaire   +3 more sources

The Treatment of Precocious Puberty

Endocrinology and Metabolism Clinics of North America, 1991
Long-acting GnRH agonists are the treatment of choice for central precocious puberty. GnRH agonists are not effective in peripheral precocious puberty, but a number of other agents, including medroxyprogesterone acetate, ketoconazole, testolactone, and androgen antagonists, may be useful.
Dennis M. Styne, Mark D. Wheeler
openaire   +3 more sources

Rapid progressive central precocious puberty: diagnostic and predictive value of basal sex hormone levels and pelvic ultrasound

Journal of Pediatric Endocrinology & Metabolism (JPEM), 2020
Objectives Data on the predictive values of parameters included in the diagnostic work-up for precocious puberty (PP) remain limited. We detected the diagnostic value of basal sex hormone levels, pelvic ultrasound parameters and bone age assessment for ...
V. Calcaterra   +8 more
semanticscholar   +1 more source

Central precocious puberty: a review of diagnosis, treatment, and outcomes.

The Lancet Child & Adolescent Health, 2023
Erika L Zevin, E. Eugster
semanticscholar   +1 more source

Gonadotropin Independent Precocious Puberty

Journal of Pediatric Endocrinology and Metabolism, 1998
Clinicians should now be fully aware of this intriguing condition of GIPP. The condition is characterized by pubertal sex steroid concentrations and gametogenesis in the presence of prepubertal or suppressed gonadotrophins. In patients with MPP especially without a family history, one should exclude the possibility of pseudoprecocious puberty due to ...
Wang, Q, Low, LCK
openaire   +4 more sources

Management of Precocious Puberty

New England Journal of Medicine, 1985
Precocious sexual development is a stressful condition for both the affected child and the family.1 Because of its relative rarity, numerous causes, and psychosocial complications, few other condit...
openaire   +3 more sources

Precocious Puberty in a Patient with Indicanuria

Journal of Pediatric Endocrinology and Metabolism, 1999
A 7-5/12 year-old girl, who was followed-up after diagnosis of indicanuria, presented with symptoms of bilateral breast enlargement. Her breast development was at Tanner stage II. No pubic or axillary hair was observed. Pelvic ultrasonography revealed multiple follicles on both ovaries.
Buyukgebiz, B   +3 more
openaire   +4 more sources

The Pathophysiology of Precocious Puberty

Hospital Practice, 1989
Advances in understanding of normal puberty have clarified many of the mechanisms underlying precocity and led in several instances to better therapy. The essential diagnostic task is to determine if the normal process has been triggered prematurely or if an abnormal process (usually inappropriate sex steroid secretion) has circumvented the normal ...
openaire   +3 more sources

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