Results 41 to 50 of about 29,943 (285)
JAMA Network Open, 2020 Key Points Question Have the annual incidence rates of central precocious puberty (CPP) and normal variant puberty (ie, premature thelarche and premature adrenarche) increased during the past 20 years in Denmark?
E. V. Bräuner +5 more
semanticscholar +1 more source
Atualização em etiologia, diagnóstico e manejo da precocidade sexual [PDF]
, 2008 Precocious puberty is defined as the development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. Gonadotropin-dependent precocious puberty (GDPP) results from the premature activation of the hypothalamic ...
ARNHOLD, Ivo J. P. +3 more
core +2 more sources
Influence of HFD-induced precocious puberty on neurodevelopment in mice
Nutrition and Metabolism, 2021 Background Precocious puberty is frequently associated with obesity, which will lead to long-term effects, especially on growth and reproduction. However, the effect of precocious puberty on children's neurodevelopment is still unknown.
Ting-bei Bo +5 more
semanticscholar +1 more source
Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]
, 2016 We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M. +7 more
core +2 more sources
Treatment of Peripheral Precocious Puberty [PDF]
, 2015 There are many etiologies of peripheral precocious puberty (PPP) with diverse manifestations resulting from exposure to androgens, estrogens, or both. The clinical presentation depends on the underlying process and may be acute or gradual.
Eugster, Erica A., Schoelwer, Melissa
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American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Limited studies have been conducted on pubertal development in populations with pre‐existing medical conditions. More than 20‐fold increased risk of early puberty has been reported in neurodevelopmental disorders; however, this is a heterogeneous group.
Amanda Piring +4 more
wiley +1 more source
Central precocious puberty: From genetics to treatment [PDF]
, 2018 Central precocious puberty (CPP) results from early activation of the hypothalamic - pituitary -gonadal (HPG) axis and follows the same sequence as normal puberty.
Eugster, Erica A. +1 more
core +1 more source
Indian Journal of Endocrinology and Metabolism, 2012 Precocious puberty in girls can be due to number of factors of which idiopathic central precocious puberty is the most common etiology. Here, we describe 3 cases of precocious puberty where the first case had premature thelarche in the background history of mother with Type 2 Diabetes Mellitus, cases 2 and 3 had ovarian tumours with heterogeneity in ...
Ariachery C. Ammini +2 more
openaire +4 more sources
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT The effect of estrogen deficiency on bone health in Turner syndrome (TS) may be a concern even before adulthood. Previous guidelines have discussed hormone replacement therapy (HRT) in children with TS. However, some practical issues related to puberty induction in TS require clarification, such as how to implement HRT to achieve adequate bone
Yukihiro Hasegawa +6 more
wiley +1 more source
European Journal of Endocrinology, 2020 Pubertal timing is regulated by the complex interplay of genetic, environmental, nutritional and epigenetic factors. Criteria for determining normal pubertal timing, and thus the definition of precocious puberty, have evolved based on published ...
S. Roberts, U. Kaiser
semanticscholar +1 more source