Results 111 to 120 of about 50,528 (188)
Journal of Hematology & OncologyEarly T-cell precursor lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) is a distinct subtype of T-ALL/LBL, characterized by a poor response to initial chemotherapy, a high relapse rate, and an inferior outcome.
Jieping Lin +14 more
doaj +1 more source
EXECUTIVE CONTROL ABILITIES AND SELF-REGULATION IN SURVIVORS OF CHILDHOOD ACUTE LYMPHOCYTIC LEUKEMIA [PDF]
Khyber Medical University Journal, 2018 OBJECTIVE: To examine executive control and self-regulation abilities in survivors of childhood acute lymphocytic leukemia (ALL). METHODS: In this cross-sectional study, thirty-five survivors of childhood ALL from Sahukat Khanum Memorial Cancer ...
Amara Gul, Sadia Zafar
doaj
Global Stability of McKeithan's Kinetic Proofreading Model for T-Cell Receptor Signal Transduction [PDF]
arXiv, 1999 This note presents a self-contained and streamlined exposition of chemical-network results due to Feinberg, Horn, and Jackson. As an application, it shows the global asymptotic stability to equilibria of McKeithan's kinetic proofreading model for T-cell receptor signal transduction.
arxiv
Automated Immunophenotyping Assessment for Diagnosing Childhood Acute Leukemia using Set-Transformers [PDF]
arXivAcute Leukemia is the most common hematologic malignancy in children and adolescents. A key methodology in the diagnostic evaluation of this malignancy is immunophenotyping based on Multiparameter Flow Cytometry (FCM). However, this approach is manual, and thus time-consuming and subjective. To alleviate this situation, we propose in this paper the FCM-
arxiv
OncoTarget, 2016 T cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL/LBL) is a precursor T cell leukemia/lymphoma that represents approximately 15% of all childhood and 25% of adult acute lymphoblastic leukemia.
D. Habiel +7 more
semanticscholar +1 more source
gghic: A Versatile R Package for Exploring and Visualizing 3D Genome Organization [PDF]
arXivMotivation: The three-dimensional (3D) organization of the genome plays a critical role in regulating gene expression and maintaining cellular homeostasis. Disruptions in this spatial organization can result in abnormal chromatin interactions, contributing to the development of various diseases including cancer.
arxiv
Control of human immune response function by T-cell population fluctuation and relaxation dynamics [PDF]
arXiv, 2015 Clinical studies have indicated that in malignant surveillances fluctuations in the population of certain effector T-cell repertoire become suppressed. Motivated by such observations and in an attempt to quantify adaptive human response to pathogens, we define an immune response function (IMRF) in terms of mean square fluctuations of T-cell ...
arxiv
Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Transfer Learning for T-Cell Response Prediction [PDF]
arXivWe study the prediction of T-cell response for specific given peptides, which could, among other applications, be a crucial step towards the development of personalized cancer vaccines. It is a challenging task due to limited, heterogeneous training data featuring a multi-domain structure; such data entail the danger of shortcut learning, where models ...
arxiv
Optimizing CAR-T Cell Manufacturing Processes during Pivotal Clinical Trials
Molecular Therapy: Methods & Clinical Development, 2020 Tisagenlecleucel is a CD19-specific chimeric antigen receptor (CAR)-T cell therapy approved for patients aged ≤25 years with relapsed or refractory B cell precursor acute lymphoblastic leukemia (B-ALL) and adults with relapsed or refractory diffuse large
Seshu Tyagarajan +2 more
doaj