Results 141 to 150 of about 6,504,273 (325)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

MarineFlux ICOADS Air‐Sea Fluxes: 1990–2020

Geoscience Data Journal
Bulk turbulent heat and momentum fluxes are derived from individual marine reports from ships and moored buoys. The source dataset is the International Comprehensive Ocean–Atmosphere Data Set (ICOADS), specifically release 3.1.0 (1990–2014) and release 3.
S. R. Smith, A. Lovett, M. A. Bourassa, M. Castells   +3 more
doaj   +1 more source

Prediction of skin sensitization potency sub-categories using peptide reactivity data

, 2017
Britta Wareing, Daniel Urbisch, Susanne N. Kolle, Naveed Honarvar, Ursula G. Sauer, Annette Mehling, Robert Landsiedel   +6 more
openalex   +1 more source

Application of an Artificial Neural Network in Reactor Thermohydraulic Problem: Prediction of Critical Heat Flux [PDF]

, 2002
Guanghui Su, Kenji Fukuda, Jia Dounan, Koji Morita   +3 more
openalex   +1 more source

Sign language recognition through Leap Motion controller and input prediction algorithm

, 2021
Daniyar Enikeev, Светлана Мустафина   +1 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

VaccineDA: Prediction, design and genome-wide screening of oligodeoxynucleotide-based vaccine adjuvants [PDF]

, 2015
Gandharva Nagpal, Sudheer Gupta, Kumardeep Chaudhary, Sandeep Kumar Dhanda, Satya Prakash, Gajendra P. S. Raghava   +5 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Prediction model for tube feeding dependency during chemoradiotherapy for at least four weeks in head and neck cancer patients: A tool for prophylactic gastrostomy decision making [PDF]

, 2019
Anna C. H. Willemsen, Annemieke Kok, Sander M. J. van Kuijk, Laura W. J. Baijens, Remco de Bree, Lot A. Devriese, Frank Hoebers, Roy Lalisang, Annemie M.W.J. Schols, Chris H.J. Terhaard, Ann Hoeben   +10 more
openalex   +1 more source