Results 181 to 190 of about 1,741,048 (219)

Improving multi-trait genomic prediction using synthetic traits from hyperspectral data based on co-heritability. [PDF]

Theor Appl Genet
Upadhyay A, Azam R, Yuan M, Ivanovic S, Ferguson JN, Paul RE, Koyejo S, El-Kebir M, Lipka AE, Leakey ADB, Fernandes SB.   +10 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

KAN-GIN: Adaptive Nonlinear Molecular Representation Learning for Drug-Target Affinity Prediction. [PDF]

Pharmaceuticals (Basel)
Bedoui A, Duraisamy N, Cherkaoui M.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Artificial Intelligence for Perioperative Risk Prediction in Anesthesiology: A Bibliometric and Knowledge-Mapping Analysis. [PDF]

Healthcare (Basel)
Özkılıç M.
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

High-precision temperature-strain composite sensing based on a single resonator-type surface acoustic wave sensor using machine learning algorithms. [PDF]

Microsyst Nanoeng
Cheng C, Liu Y, Yang J, Luo T, Tong T, Luo C, Li X, Fang X, Ke Q.   +8 more
europepmc   +1 more source

Physics-guided residual learning for phase-aware UAV trajectory prediction in urban environments. [PDF]

Sci Rep
Islam MA, Förster S, Zhang T, Fricke H.
europepmc   +1 more source