Results 91 to 100 of about 563,114 (266)

To update or to separate: Neural signatures and consequences of latent cause inference in episodic memory

NeuroImage
Episodic memories are leveraged to predict upcoming input. Latent Cause Theory (Gershman et al., 2017) predicts that after moderate prediction errors, existing memories will be updated by integrating new information, while after large prediction errors ...
Marius Boeltzig, Sophie Siestrup, Inês Bramão, Ricarda I. Schubotz   +3 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Predictive coding in psychopathology: mechanistic model or metaphorical re-description?

Frontiers in Human Neuroscience
Predictive coding (PC) has become a central framework in contemporary cognitive neuroscience, proposing that the brain operates as a hierarchical inference system that continuously minimizes the mismatch between predicted and actual sensory input.
Albandri Sultan Alotaibi
doaj   +1 more source

Accuracy of new and standard intraocular lens power calculations formulae in Saudi pediatric patients

Taiwan Journal of Ophthalmology, 2019
PURPOSE: The purpose of this study is to compare the accuracy of new generation formulas to standard formulas for intraocular lens (IOL) power calculations in pediatric patients.
Fouad Raja an-Nakhli
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Wait for it: Predicted Error vs. Prediction Error in Language Processing

, 2016
Poster presented at 2015 meeting of the Society for the Neurobiology of ...
Alday, Phillip M., Sassenhagen, Jona, Coussens, Scott, Bornkessel-schlesewsky, Ina   +3 more
openaire   +1 more source

Prediction of discretization error using the error transport equation

Journal of Computational Physics, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ismail B. Celik, Don Roscoe Parsons III
openaire   +3 more sources

Variational free energy as a conceptual framework for understanding habituation in spinal cord stimulation

Frontiers in Pain Research
IntroductionHabituation, or loss of clinical benefit over time, is a frequent problem in spinal cord stimulation (SCS). Existing programming strategies such as waveform cycling or closed-loop stimulation try to address it, but there is no common ...
Alexander Taghva, Alexander Taghva
doaj   +1 more source

The Implementation of Predictions During Sequencing

Frontiers in Cellular Neuroscience, 2019
Optimal control mechanisms require prediction capabilities. If one cannot predict the consequences of a motor act or behavior, one will continually collide with walls or become a social pariah.
M. Molinari, M. Masciullo
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source