Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine
We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman +7 more
wiley +1 more source
Enhancing collision prediction in older adults via perceptual training in virtual reality emphasizing object expansion. [PDF]
Sato K, Higuchi T.
europepmc +1 more source
An integrated perfusion‐based culture platform combining pre‐vascularized collagen scaffolds, stromal vascular fraction cells, and kidney decellularized extracellular matrix promotes vascularization of human iPSC‐derived kidney organoids. The platform provides evidence of interactions between vascular networks and glomerular‐like structures and enables
Helen Kearney +5 more
wiley +1 more source
A novel interval prediction method with adaptive calibration for ship energy consumption prediction. [PDF]
Hu Z +7 more
europepmc +1 more source
Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley +1 more source
Prediction of Composite Supercapacitor Performance Through Combining Machine Learning with Novel Binder-Related Features. [PDF]
Gong T, Yu W, Wang X.
europepmc +1 more source
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
Enhancing multi-component alloy composition prediction based on generative adversarial networks and proximal policy optimization. [PDF]
Zhang SL, Bai SB, Shang WJ, Liu Q, Yu P.
europepmc +1 more source
Data-driven model reveals increased stability of CAG-expanded huntingtin RNA due to MID1 binding. [PDF]
Liu Y +5 more
europepmc +1 more source
Interpretable QSAR and Complementary Docking for PARP1 Inhibitor Prioritization: Reliability Stratification and Near-Domain Screening. [PDF]
Elsayad AM, Elsayad KA.
europepmc +1 more source

