Results 211 to 220 of about 4,112,292 (287)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Analysis of risk factors and establishment of a prediction model for latent autoimmune diabetes in adults. [PDF]

Ther Adv Endocrinol Metab
Yan H, Lv J, Miao L, Shi L.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Multicenter Prospective Validation of an Updated Proprietary Sepsis Prediction Model.

JAMA Netw Open
Wong A, Currey D, Schwinne M, Park-Egan B, Meyer S, Gutting A, Cao J, Khan S, Dantes R, Pan T, Buchman T, Singh K, Bhavani SV, Lyons PG, Sjoding MW, Tarabichi Y.   +15 more
europepmc   +1 more source

Postoperative pulmonary complications after esophagectomy: risk factors and prediction model. [PDF]

Dis Esophagus
van der Aa DC, Khatib R, Eshuis WJ, Daams F, Gisbertz SS, van Berge Henegouwen M.   +5 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Recent Enhancements to the Genetic Risk Prediction Model BRCAPRO

Cancer Informatics, 2015
Emanuele Mazzola, Amanda Blackford, Giovanni Parmigiani, Swati Biswas   +3 more
doaj  

Novel biomarker-based prediction model for coronary artery lesions in Kawasaki disease. [PDF]

BMC Pediatr
Wang M, Deng J, Cai C, Liu B, Zhang X.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Risk Prediction Model for Taxane-Induced Peripheral Neuropathy in Early-Stage Cancer.

JAMA Netw Open
Trivedi MS, Unger JM, Henry NL, Darke AK, Hertz DL, Brannagan TH, Reyes SJ, Schneider BP, Irvin WJ, Hathaway AR, Vander Woude AC, Gudena VK, Cabrera-Galeana P, Orsted M, LeBlanc M, Fisch MJ, Hershman DL.   +16 more
europepmc   +1 more source