Results 111 to 120 of about 167,767,624 (293)

Numerical simulation of the interaction between mine water drainage and recharge: A case study of Wutongzhuang coal mine in Heibei Province, China

Ecological Indicators
Water inflow poses a critical safety concern in coal mining. The pressing challenge in current mine water inflow research is the need to enhance the prediction of dynamic changes in mine water inflow across different mining stages.
Bin Liu, Guanghui Liu, Jinxia Sha, Jianwei Sun, Xian Zhao, Shuai Ren, Ruiting Liu, Su Li   +7 more
doaj   +1 more source

Epithelial SLC25A20 Deficiency Drives Immunosuppressive Neutrophil Remodeling via ARG1 Palmitoylation to Promote Colorectal Cancer

Advanced Science, EarlyView.
SLC25A20 deficiency in tumor cells compromises mitochondrial LCFA transport, which suppresses FAO and drives compensatory release of palmitic acid‐enriched lipids into the TME. These tumor‐derived palmitic acids are taken up by TANs, promoting ZDHHC18‐catalyzed ARG1 palmitoylation.
Yue Han, Tian‐Yuan Tan, Bin Zhang, Ye‐Bin Fu, Wen Chen, Min‐Hui Yang, Yi‐Qing Wang, Yan‐Qing Ding, Shuang Wang   +8 more
wiley   +1 more source

Summary of a Report on Geothermal Water Resources in Arizona: Feasibility Study

, 1977
Published in cooperation with Arizona Water Commission and Office of Arid Lands Studies, University of Arizona.INTRODUCTION: Arid lands will undoubtedly experience increased energy stresses in the near future because of increasing internal populations ...
Norton, Denis L., Sumner, John S., DeCook, K. James, Gerlach, Terrence M.   +3 more
core  

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

Angewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej, Arturo Rodríguez‐Banqueri, Danuta Mizgalska, Borys Szmigielski, Zuzanna Nowakowska, Małgorzata Benedyk‐Machaczka, Monika Bzowska, Katarzyna Mikruta, Juan Sebastián Ramírez‐Larrota, Chinanu Agunanne, Olivier Julien, Anthony J. O'Donoghue, Carsten Scavenius, Mario López‐Martín, Enrique Marcos, Łukasz Koziej, Sebastian Glatt, Pablo Guerra, Ulrich Eckhard, Jan Potempa, F. Xavier Gomis‐Rüth   +20 more
wiley   +2 more sources

Long-term inflow forecast using meteorological data based on long short-term memory neural networks

Journal of Hydroinformatics
Long-term inflow forecasting is extremely important for reasonable dispatch schedules of hydropower stations and efficient utilization plans of water resources.
Hongye Zhao, Shengli Liao, Yitong Song, Zhou Fang, Xiangyu Ma, BinBin Zhou   +5 more
doaj   +1 more source

3D Bioprinted Blood–Brain–Tumor Barrier Spheroid‐Based In Situ Evaluation of Anticancer Compounds Against Glioblastoma: ROS‐Producing Ruthenium as a Potential Therapeutic Candidate

Advanced Science, EarlyView.
The blood–brain–tumor barrier (BBTB) penetration by anticancer drugs and their effects on glioblastoma (GBM) is assessed using 3D bioprinted‐spheroids. Anticancer drug‐induced U‐87 MG cell death is quantified through in situ imaging of spheroids using a cancer cell death probe. The Ru compound, a partial P‐gp substrate, induces greater tumor‐cell death
Hyunjung Lee, Chan Ho Jeon, Doyun Kim, Minjae Lee, Minji Kwon, Joon Myong Song   +5 more
wiley   +1 more source

Movement of water from canals to groundwater table; Research technical completion report project A-009-Ida

, 1968
Investigation of the mechanics of water movement from irrigation canals to the water table has been performed on selected canals in southern Idaho.
Brockway, Charles E.; Bloomsburg, G.L.
core  

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

Advanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu, Qibo Li, Weihao Zhang, Guan Zheng, Junhua Chen, Yipeng Zeng, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Jiajie Lin, Zepeng Su, Zhongyu Xie   +12 more
wiley   +1 more source

Biological and water quality study of Big Darby Creek and selected tributaries, 2001/2002 : Logan, Champaign, Union, Madison, Franklin and Pickaway counties, Ohio.

, 2004
Title from home page (viewed on Aug. 23, 2006).; "Prepared by State of Ohio Environmental Protection Agency, Division of Surface Water ..."--PDF t.p.; "June 28, 2004."; Harvested from the web on 8/23 ...
Ohio EPA. Division of Surface Water.
core  

Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology

Advanced Science, EarlyView.
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen, Yu Tang, Chengpeng Hu, Xiaoyan Duan, LingXia Min, Boya Cong, Chao Ma, Mingliang Tan, Ya Luo, Pengfei Wei, Minpeng Xu, Zhou Feng, Jingming Hou   +12 more
wiley   +1 more source