Examining residuals such as Pearson and deviance residuals, is a standard tool for assessing normal regression. However, for discrete response, these residuals cluster on lines corresponding to distinct response values.
Feng, Cindy +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Relationship Between Acute Appendicitis and Platelet Indices in Childhood [PDF]
Introduction: Appendicitis is the inflammation of the appendix vermiformis. Clinical diagnosis of acute appendicitis in children is still a problem.
Asena Sucu +6 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mean-Field-Type Model Predictive Control: An Application to Water Distribution Networks
In this paper, we study and design a mean-field-type model predictive control, which is a class of risk-aware control considering within the cost functional not only the mean but also the variance of both the system states and control inputs. We formally
Julian Barreiro-Gomez, Hamidou Tembine
doaj +1 more source
Bayesian inference for bivariate ranks
A recommender system based on ranks is proposed, where an expert's ranking of a set of objects and a user's ranking of a subset of those objects are combined to make a prediction of the user's ranking of all objects.
Guillotte, Simon +2 more
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Selection method for observation points using Bayesian LASSO at estimating radiation source distribution from air dose rates [PDF]
When we decommission a reactor building, it is essential to identify the radiation source distribution for safety. It has been reported that the source distribution can be predicted from the measured air dose rates at appropriate observation points by ...
Yamada Susumu +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Bayesian hierarchical models for analysing the spatial distribution of bioclimatic indices [PDF]
A methodological approach for modelling the spatial distribution of bioclimatic indices is proposed in this paper. The value of the bioclimatic index is modelled with a hierarchical Bayesian model that incorporates both structured and unstructured random
Barber, Antoni +5 more
core

