Results 71 to 80 of about 1,703,012 (264)

Randomized Predictive P-values: A Versatile Model Diagnostic Tool with Unified Reference Distribution

open access: yes, 2019
Examining residuals such as Pearson and deviance residuals, is a standard tool for assessing normal regression. However, for discrete response, these residuals cluster on lines corresponding to distinct response values.
Feng, Cindy   +2 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Relationship Between Acute Appendicitis and Platelet Indices in Childhood [PDF]

open access: yesJournal of Pediatric Emergency and Intensive Care Medicine, 2018
Introduction: Appendicitis is the inflammation of the appendix vermiformis. Clinical diagnosis of acute appendicitis in children is still a problem.
Asena Sucu   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Mean-Field-Type Model Predictive Control: An Application to Water Distribution Networks

open access: yesIEEE Access, 2019
In this paper, we study and design a mean-field-type model predictive control, which is a class of risk-aware control considering within the cost functional not only the mean but also the variance of both the system states and control inputs. We formally
Julian Barreiro-Gomez, Hamidou Tembine
doaj   +1 more source

Bayesian inference for bivariate ranks

open access: yes, 2018
A recommender system based on ranks is proposed, where an expert's ranking of a set of objects and a user's ranking of a subset of those objects are combined to make a prediction of the user's ranking of all objects.
Guillotte, Simon   +2 more
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Selection method for observation points using Bayesian LASSO at estimating radiation source distribution from air dose rates [PDF]

open access: yesEPJ Web of Conferences
When we decommission a reactor building, it is essential to identify the radiation source distribution for safety. It has been reported that the source distribution can be predicted from the measured air dose rates at appropriate observation points by ...
Yamada Susumu   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Bayesian hierarchical models for analysing the spatial distribution of bioclimatic indices [PDF]

open access: yes, 2017
A methodological approach for modelling the spatial distribution of bioclimatic indices is proposed in this paper. The value of the bioclimatic index is modelled with a hierarchical Bayesian model that incorporates both structured and unstructured random
Barber, Antoni   +5 more
core  

Home - About - Disclaimer - Privacy