Results 171 to 180 of about 2,294,849 (300)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Resting energy expenditure in adolescents with Down syndrome: a comparison of commonly used predictive equations. [PDF]

J Intellect Disabil Res, 2023
Helsel BC, Shook RP, Forseth B, Dreyer Gillette ML, Polfuss M, Miller B, Posson P, Steele R, Thyfault JP, Ptomey LT.   +9 more
europepmc   +1 more source

Observation and prediction for the heat equation, II

Journal of Mathematical Analysis and Applications, 1972
Mizel, V.J, Seidman, T.I
openaire   +2 more sources

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Development and validation of new predictive equations for resting energy expenditure in physically active boys. [PDF]

Sci Rep, 2023
Łuszczki E, Jagielski P, Bartosiewicz A, Dereń K, Matłosz P, Kuchciak M, Oleksy Ł, Stolarczyk A, Mazur A.   +8 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Measured resting energy expenditure via indirect calorimetry of critically ill patients: A comparison with predictive equations. [PDF]

Asia Pac J Clin Nutr
Tian Z, Zheng Z, Wang X, Yao Y.
europepmc   +1 more source

Accuracy of predictive equations for resting energy expenditure estimation in mechanically ventilated Thai patients. [PDF]

Asian Biomed (Res Rev News), 2023
Kongpolprom N.
europepmc   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Indirect calorimetry compared with predictive equations for resting energy expenditure in patients with intestinal failure. [PDF]

Intest Fail
Wyer N, Reynolds E, Norrie L, Woodend L, Richardson H, Ferguson E.   +5 more
europepmc   +1 more source