Results 71 to 80 of about 2,281,330 (290)

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Resected stage I anaplastic lymphoma kinase‐positive lung adenocarcinoma has a negative impact on recurrence‐free survival

Thoracic Cancer, 2022
Background The clinical and prognostic implications of anaplastic lymphoma kinase (ALK) status in resected lung cancers remain unclear. In this study we analyzed the prognostic and predictive significance of ALK‐positive among patients with completely ...
Yusuke Fujibayashi, Shinya Tane, Mai Kitazume, Sanae Kuroda, Kenji Kimura, Yoshitaka Kitamura, Wataru Nishio   +6 more
doaj   +1 more source

Clinical and Genetic Risk Factors Associated with Psoriatic Arthritis among Patients with Psoriasis. [PDF]

, 2018
IntroductionPsoriatic arthritis (PsA) is a chronic, inflammatory arthritis that affects an estimated 30% of patients with psoriasis. PsA is underdiagnosed in primary care and dermatology clinics due to a variety of reasons, including failure of ...
Ahn, Richard, Leslie, Stephen, Liao, Wilson, Yan, Di   +3 more
core   +3 more sources

Context Specific Transcription Factor Prediction [PDF]

Annals of Biomedical Engineering, 2007
One of the goals of systems biology is the identification of regulatory mechanisms that govern an organism's response to external stimuli. Transcription factors have been hypothesized as a major contributor to an organism's response to various outside stimuli, and a great deal of work has been done to predict the set of transcription factors which ...
Eric, Yang, David, Simcha, Richard R, Almon, Debra C, Dubois, William J, Jusko, Ioannis P, Androulakis   +5 more
openaire   +2 more sources

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Gangs, Guns, and Drugs: Recidivism among Serious, Young Offenders [PDF]

, 2007
The primary goal of this study is to understand the factors that best explain recidivism among a sample of 322 young men aged 17 to 24 years released from prison in a Midwestern state.
Adams, Akers, Anderson, Battin-Pearson, Benda, Blumstein, Braga, Bushway, Chaiken, Clemmer, Coleman, Cook, Cook, Cork, Cox, Decker, Decker, Decker, DeJong, Esbensen, Esbensen, Fagan, Fagan, Flannery, Fleisher, Fowler, Gendreau, Giordano, Glaze, Gottfredson, Griffin, Griffin, Hagan, Hariston, Harrison, Hirschi, Holtfreter, Huebner, Huebner, Huff, Hughes, Kennedy, Klein, Kubrin, Langan, Lattimore, Lattimore, Laub, Laub, Lizotte, Loeber, Lynch, Maltz, Maruna, Maruna, Matsueda, McDevitt, McGarrell, Mumola, Nurse, Olson, Pager, Papachristos, Perkins, Petersilia, Rosenfeld, Sampson, Sampson, Sheley, Shover, Singer, Spohn, Sykes, Uggen, Visher, Visher, Wacquant, Warr, Western, Western, Wintemute, Wright, Wright, Zamble   +83 more
core   +3 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Predicting time to graduation at a large enrollment American university

, 2020
The time it takes a student to graduate with a university degree is mitigated by a variety of factors such as their background, the academic performance at university, and their integration into the social communities of the university they attend ...
Aiken, John M., Caballero, Marcos D., De Bin, Riccardo, Hjorth-Jensen, Morten   +3 more
core   +1 more source