Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
The Predictive Validity of Marijuana Odor Detection: An Examination of Alaska State Trooper Case Reports 2006–2010 [PDF]
This study provides an empirical estimate of the extent to which Alaska State Troopers (AST) investigators’ detection of marijuana odors served as a reliable indicator of the presence of illegal quantities of marijuana in suspected structures/buildings ...
Brandeis, Jason, Myrstol, Brad A.
core
Associated lesions in posterior wall acetabular fractures: not a valid predictor of failure [PDF]
Lukas D. Iselin +4 more
openalex +1 more source
Predictive Validity of a Medication Adherence Measure in an Outpatient Setting
D. Morisky +3 more
semanticscholar +1 more source
Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan +3 more
wiley +1 more source
Objective:To explore the predictive validity of Functional Capacity Evaluation(FCE)on the employment status of work-related injured patients at different injured sites, and to explore the effect of pain on the predictive validity.Methods:A total of 300 ...
Ru HUANG +3 more
doaj
A test of the predictive validity of non-linear QALY models using time trade-off utilities [PDF]
This paper presents a test of the predictive validity of various classes of QALY models (i.e., linear, power and exponential models). We first estimated TTO utilities for 43 EQ-5D chronic health states and next these states were embedded in health ...
Ildefonso Méndez +3 more
core
Comparing the predictive validity of DUI risk screening instruments: development of validation standards [PDF]
Bradley J. Anderson +2 more
openalex +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source

