Results 191 to 200 of about 7,602,490 (304)

Positive Predictive Value of Universal Cardiovascular Disease Risk Assessment for Pregnant and Postpartum Patients. [PDF]

JACC Adv
Wolfe DS, Hameed AB, Black KE, Chang J, Grodzinsky A, Tarsa M, Florio KL, Graves CR, Thiel de Bocanegra H.   +8 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study. [PDF]

Ann Clin Transl Neurol
Wu B, Li JJ, Jing J, Lin JX, Meng X, Jiang Y, Wang YJ, Gu HQ.   +7 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Negative Predictive Value of Allergologic Work-Up with Iodinated Contrast Media in 'Real-Life' Practice. [PDF]

J Clin Med
Specjalski K, Iwaszko I, Typiak D, Juszkiewicz D, Szablewska W, Skotnicki M, Le N, Powietrzyński M, Strukowski A, Śledzik J, Chełmińska M, Niedoszytko M.   +11 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The distinguished predictive value of CFIm25 in schistosomal and non-schistosomal colorectal cancer. [PDF]

Transl Cancer Res
Chai S, Zhang Y, Zhang X, Liu L, Jing H, Wang W, Qin Y.   +6 more
europepmc   +1 more source

Predictive Value of In-Service Exams

Family Medicine, 2023
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Predictive value of remnant cholesterol for in-stent restenosis after drug-eluting stent implantation. [PDF]

Medicine (Baltimore)
Yimamu A, Yang H, Feng W, Wufuli Z, Tuersun T.   +4 more
europepmc   +1 more source