Results 161 to 170 of about 936,691 (247)

Recurrence risk prediction model for hepatitis B virus-associated hepatocellular carcinoma patients: a systematic review and meta-analysis. [PDF]

Front Oncol
Zhao KH, Liu J, Chen YS, Yi WT, Liu JJ, Zeng Y.   +5 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Disentangling the effects of multifunctional forestry practices on the abundances of birds and their invertebrate prey. [PDF]

Ecol Appl
Cordeiro Pereira JM, Klingenfuß S, Basile M, Frey J, Mikusiński G, Storch I.   +5 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Comparing Risk Prediction for Suicide Attempts and Deaths After Emergency Department Visits for Individuals With Mental Health Disorders. [PDF]

J Clin Psychiatry
Marcus SC, Wiesel Cullen S, Xie M, Liu T, Williams NJ, Schmutte T, Ungar LH, Cardamone NC, Olfson M.   +8 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Shaping science: Scholarly motivation and research outcomes in NIH-HEAL funded studies. [PDF]

PLoS One
Kushmerick-McCune B, Sawyer-Morris G, Ulukaya M, Clark K, Walters ST, Taxman FS.   +5 more
europepmc   +1 more source

Predictors and indicators

Korean Journal of Anesthesiology
openaire   +3 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Climate predictors of child undernutrition: Insights from a machine learning model. [PDF]

PLoS One
Essiam FAAP, Amoako M, Issah S, Biney M, Akuffo KO, Amekudzi LK.   +5 more
europepmc   +1 more source