Results 211 to 220 of about 32,530 (244)

Predominant polarity in bipolar disorder patients: The COPE bipolar sample [PDF]

Journal of Affective Disorders, 2019
The concept of predominant polarity (PP) is defined as presenting more symptoms of one polarity. Previous studies have defined PP as one polarity (either a depression or mania episode) occurring during at least two-thirds of the lifetime.We conducted an observational study with the COPE-BD (Clinical Outcome and Psycho-Education for Bipolar Disorder ...
Othman Sentissi, Dina Popovic, Clotilde Moeglin   +2 more
exaly   +5 more sources

Predominant polarity and temperament in bipolar and unipolar affective disorders

Journal of Affective Disorders, 2009
Recently, the concept of predominant polarity (two-thirds of episodes belonging to a single pole of the illness) has been introduced to further characterise subtypes of bipolar disorders. This concept has been proven to have diagnostic and therapeutic implications, but little is known on the underlying psychopathology and temperaments. With this study,
Lorenzo Mazzarini, Isabella Pacchiarotti, Francesc Colom   +2 more
exaly   +4 more sources

Predominant polarity and hippocampal subfield volumes in Bipolar disorders [PDF]

Bipolar Disorders, 2019
AbstractObjectivesPredominant polarity (PP) is a proposed course specifier for bipolar disorders (BD) based on patient lifetime mood episodes. Hippocampal subfield volumetric changes have been proposed as a neurobiological marker for BD and could be influenced by mood episodes.
Janiri D., Simonetti A., Piras F., Ciullo V., Spalletta G., Sani G.   +5 more
core   +7 more sources

Predominant polarity, polarity index, and treatment selection in bipolar disorder

, 2017
Bipolar disorder (BD) is a chronic and disabling illness, with lifetime prevalence of 2.4% worldwide. Predominant polarity (PP), ie, depressive versus manic, may influence illness characteristics, treatment selection, and outcomes in BD. PP has been proposed as a course specifier for BD, although not included in the Diagnostic and Statistical Manual of
Sabrina C. da Costa, Joao L. de Quevedo, André F. Carvalho   +2 more
openaire   +2 more sources

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Clinical and therapeutic implications of predominant polarity in bipolar disorder

Journal of Affective Disorders, 2006
To determine the clinical and therapeutic relevance of longitudinally predominant polarity for bipolar disorders long-term outcome.Two hundred twenty-four patients (n=224) were enrolled for the study in the Bipolar Disorders Program of Barcelona, which provides integrated care for difficult-to-treat bipolar patients derived from all over Spain, but ...
Francesc Colom, Eduard Vieta, Isabella Pacchiarotti   +2 more
exaly   +3 more sources

Predominant polarity in bipolar disorders: Further evidence for the role of affective temperaments

Journal of Affective Disorders, 2015
Literature suggests bipolars may differ in several features according to predominant polarity, but the role of temperaments remains controversial.The EPIDEP study was designed to identify bipolar patients among a large sample of major depressives. Only bipolars were included in the current study.
J M Azorín, M Adida, R Belzeaux
exaly   +3 more sources

Gender differences in a cohort study of 604 bipolar patients: The role of predominant polarity

Journal of Affective Disorders, 2011
Some clinical differences between gender regarding the course and outcome of bipolar disorders have already been described and some others remain still controversial.To explore gender differences regarding clinical and socio-demographic characteristics amongst bipolar patients with particular attention to predominant polarity and depressive symptoms ...
NIVOLI, Alessandra, Pacchiarotti I, Rosa AR, Popovic D, Murru A, Valenti M, Bonnin CM, Grande I, Sanchez Moreno J, Vieta E, Colom F.   +10 more
openaire   +3 more sources

Predominant regulators of tubulin monomer–polymer partitioning and their implication for cell polarization

Cellular and Molecular Life Sciences, 2009
The microtubule-system organizes the cytoplasm during interphase and segregates condensed chromosomes during mitosis. Four unrelated conserved proteins, XMAP215/Dis1/TOGp, MCAK, MAP4 and Op18/stathmin, have all been implicated as predominant regulators of tubulin monomer-polymer partitioning in animal cells. However, while studies employing the Xenopus
Holmfeldt P, Sellin ME, Gullberg M
openaire   +4 more sources

Treatment Implications of Predominant Polarity and the Polarity Index: A Comprehensive Review [PDF]

International Journal of Neuropsychopharmacology, 2015
BACKGROUND: Bipolar disorder (BD) is a serious and recurring condition that affects approximately 2.4% of the global population. About half of BD sufferers have an illness course characterized by either a manic or a depressive predominance.
André F Carvalho, João Quevedo, Roger S Mcintyre   +2 more
exaly   +2 more sources

The biological basis of predominant polarity

, 2021
Isabella Pacchiarotti, Gerard Anmella, Eduard Vieta   +2 more
openaire   +2 more sources