Results 51 to 60 of about 99,397 (272)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Photo- and solvatochromic properties of nitrobenzospiropyran in ionic liquids containing the [NTf2]- anion [PDF]

, 2008
The photo-, thermo- and solvatochromic properties of 2,3-dihydro-10,30,30-trimethyl-6-nitrospiro- [1-benzopyran-2,20-1H-indole] (BSP-NO2) were studied in ILs containing the anion [NTf2]- by UV-Vis absorption spectroscopy, ab initio molecular orbital ...
Byrne, Robert, Diamond, Dermot, Forsyth, Maria, Fraser, Kevin J., Izgorodina, Ekaterina, MacFarlane, Douglas R.   +5 more
core   +1 more source

Influence of Solvent Polarity on the Kinetics of Microwave-assisted Extraction, Composition, and Antiradical Activity of Black Locust Flowers (Robinia pseudoacacia flos) Extracts [PDF]

Chemical and Biochemical Engineering Quarterly
The present study investigated the influence of solvent polarity on the kinetics of microwave-assisted extraction of phenolic compounds from black locust flowers.
I. M. Savic, I. A. Boskov, I. M. Savic Gajic   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Automated Coronal Hole Detection using Local Intensity Thresholding Techniques

, 2009
We identify coronal holes using a histogram-based intensity thresholding technique and compare their properties to fast solar wind streams at three different points in the heliosphere.
A. Kavanagh, A.F. Timothy, A.S. Krieger, C.E. DeForest, C.J. Henney, C.J. Schrijver, D. Odstrcil, D.M. Hassler, E. Antonucci, E.M. Reeves, G.D. Toma, G.S. Vaiana, I.F. Scholl, I.I. Roussev, J.G. Luhmann, J.P. Delaboudinière, K. Fujiki, K. Wilhelm, K.L. Harvey, L. Golub, L.M. Blush, Larisza D. Krista, M. Guhathakurta, M. Temmer, M.C. Chiu, M.D. Altschuler, N.A. Schwadron, N.R. Sheeley Jr., O.V. Malanushenko, P.H. Scherrer, P.T. Gallagher, P.T. Gallagher, Peter T. Gallagher, R. Kano, R. Lionello, R.A. Harrison, R.C. Gonzalez, R.H. Munro, R.T.J. McAteer, S. Belkasim, S.A. Chapman, S.K. Antiochos, S.L. Freeland, T. Wiegelmann, T. Wiegelmann, Y.M. Wang, Y.M. Wang, Y.V. Pisanko   +47 more
core   +1 more source

Research Progress on PATJ and Underlying Mechanisms Associated with Functional Outcomes After Stroke

Neuropsychiatric Disease and Treatment, 2021
Wen-Jie Wang,1 Tian-Jie Lyu,2,3 Zixiao Li1– 5 1Vascular Neurology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, People’s Republic of China; 2China National Clinical Research Center for Neurological ...
Wang WJ, Lyu TJ, Li Z
doaj  

Assessing progression in Bipolar Disorder: a staging model tested in a sample over ten years of observation

European Psychiatry, 2023
Introduction The longitudinal course of bipolar disorder (BD) is related to an active process of neuroprogression, associated with brain changes and functional impairment (Berk et al., Bipolar Disord 2014; 16(5):471-7).
N. Girone, M. Macellaro, L. Cremaschi, M. Bosi, B. M. Cesana, F. Ambrogi, B. Dell’Osso   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Coordinated functional divergence of genes after genome duplication in Arabidopsis thaliana [PDF]

, 2017
Gene and genome duplications have been rampant during the evolution of flowering plants. Unlike small-scale gene duplications, whole-genome duplications (WGDs) copy entire pathways or networks, and as such create the unique situation in which such ...
De Smet, Riet, Li, Zhen, Sabaghian, Ehsan, Saeys, Yvan, Van de Peer, Yves   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source