Results 101 to 110 of about 243,277 (388)

Pregnancy outcomes in women with systemic sclerosis before and/or after diagnosis, and by parity ‐ A Swedish population‐based cohort study

Arthritis &Rheumatology, Accepted Article.
Objective To assess risks of adverse pregnancy outcomes (APO) in a contemporary cohort of women with systemic sclerosis (SSc) in relation to the timing of SSc diagnosis and by parity. Methods From the nationwide Swedish Medical Birth Register, we assembled pregnancies with births in women with SSc and in comparator women from the general population ...
Weng Ian Che, Luigi Annicchiarico, Laura Andreoli, Olof Stephansson, Marie Holmqvist, Karin Hellgren   +5 more
wiley   +1 more source

Predicting Preeclampsia with Noninvasive Measures of Endothelial Dysfunction: A Pilot Study

American Journal of Perinatology Reports, 2020
Objective This study evaluates the assessment of endothelial function and its prediction for preeclampsia among women with high-risk factors. Study Design A prospective cohort study of 107 pregnant women at 20 weeks or greater gestation with ...
Emmanuel U. Emeasoba, Rodney A. McLaren Jr., Rebecca Landau, Jeremy Weedon, Shoshana Haberman, Howard Minkoff, Jacob Shani, Nadine Montemarano   +7 more
doaj   +1 more source

Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats [PDF]

, 2018
Hypertensive disorders of pregnancy are the second leading cause of maternal deaths worldwide. Superimposed preeclampsia is an increasingly common problem and often associated with impaired placental perfusion. Understanding the underlying mechanisms and
Beattie, Elisabeth, Butler, Elaine, Dechend, Ralf, Graham, Delyth, Herse, Florian, McBride, Martin W., Morgan, Hannah L., Ritchie, Shona   +7 more
core   +2 more sources

Preeclampsia: Risk Factors, Diagnosis, Management, and the Cardiovascular Impact on the Offspring

Journal of Clinical Medicine, 2019
Hypertensive disorders of pregnancy affect up to 10% of pregnancies worldwide, which includes the 3%–5% of all pregnancies complicated by preeclampsia. Preeclampsia is defined as new onset hypertension after 20 weeks’ gestation with evidence of maternal ...
R. Fox, J. Kitt, P. Leeson, C. Aye, A. Lewandowski   +4 more
semanticscholar   +1 more source

The Association Between Maternal Asthma and Child Autism: A Systematic Review and Meta‐Analysis

Autism Research, EarlyView.
ABSTRACT Maternal asthma has been linked to child autism. In this study, we systematically reviewed observational studies published between July 2001 and February 2024 that assessed maternal asthma during pregnancy (exposure) and child autism (outcome). Databases searched included MEDLINE, CINAHL, EMBASE, and PsycINFO.
Renee van der Schaaf, Vanessa E. Murphy, Soriah Harvey, Paige Dent, Alison Lane, Olivia Whalen   +5 more
wiley   +1 more source

Inherited factors contribute to an inverse association between preeclampsia and breast cancer

Breast Cancer Research, 2018
Background Preeclampsia is frequently linked to reduced breast cancer risk. However, little is known regarding the underlying genetic association and the association between preeclampsia and mammographic density.
Haomin Yang, Wei He, Mikael Eriksson, Jingmei Li, Natalie Holowko, Flaminia Chiesa, Per Hall, Kamila Czene   +7 more
doaj   +1 more source

Metabolomics application in maternal-fetal medicine [PDF]

, 2013
Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L, Fanos, V, Ferrazzi, E, Makarenko, K, Melis, GB   +4 more
core   +4 more sources

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Early onset preeclampsia is characterized by altered placental lipid metabolism and a premature increase in circulating FABP4 [PDF]

, 2010
Preeclampsia is a pregnancy-associated disorder that manifests as a sudden increase in maternal blood pressure accompanied by proteinuria. Because the placenta is a key organ in preeclampsia, we used proteomic and lipidomic analyses to compare placentae ...
Aaron Booy, Delfina Siroen, Gilles Lajoie, Jennifer Ballard, Nicholas Carruthers, Victor H. Han   +5 more
core   +1 more source

Preeclampsia and risk of breast cancer: A longitudinal cohort study of tumor histology

International Journal of Cancer, EarlyView.
What's New? Preeclampsia is protective against breast cancer, but it is not clear if the effect extends to all breast tumors. This study examined the association between preeclampsia and breast tumor histology. The findings suggest that the protective effect of preeclampsia is concentrated among ductal and lobular tumors, but not other tumors. Patients
Shu Qin Wei, Valérie Leduc, Brian Potter, Gilles Paradis, Aimina Ayoub, Jessica Healy‐Profitós, Amanda Maniraho, Antoine Lewin, Nathalie Auger   +8 more
wiley   +1 more source