Results 151 to 160 of about 243,277 (388)

Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?

British Journal of Pharmacology, EarlyView., 2023
Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley   +1 more source

Autoimmune conditions and comorbid depression in pregnancy: examining the risk of preterm birth and preeclampsia. [PDF]

, 2017
ObjectiveThe objective of this study was to determine whether prenatal depression interacts with autoimmune conditions to further increase the risk of preterm birth or preeclampsia.Study designOur sample included 3034 pregnant women with rheumatoid ...
Bandoli, G, Chambers, CD
core   +1 more source

Preeclampsia: The Relationship between Uterine Artery Blood Flow and Trophoblast Function

International Journal of Molecular Sciences, 2019
Maternal uterine artery blood flow is critical to maintaining the intrauterine environment, permitting normal placental function, and supporting fetal growth. It has long been believed that inadequate transformation of the maternal uterine vasculature is
A. Ridder, V. Giorgione, A. Khalil, B. Thilaganathan   +3 more
semanticscholar   +1 more source

Prevention of preeclampsia [PDF]

Journal of Clinical Investigation, 2016
Preeclampsia is a common complication of pregnancy that is associated with an increased risk of maternal and neonatal morbidity and mortality. Currently, delivery is the only cure for preeclampsia; therefore, effective prevention and treatment options for this condition are sorely needed. In the current issue of the JCI, Mirzakhani et al.
openaire   +3 more sources

Towards the Development of a Conceptual Framework of the Determinants of Pre‐eclampsia: A Hierarchical Systematic Review of Biomarkers

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Pre‐eclampsia is a leading cause of maternal and perinatal morbidity and mortality. There are several determinants of individual pregnant women's risk of developing pre‐eclampsia, including biomarkers and ultrasound markers. Objective A conceptual framework to collate and summarise the extensive body of literature on biomarkers ...
Terteel Elawad, Hiten D. Mistry, Mai‐Lei Woo Kinshella, Marianne Vidler, Marie‐Laure Volvert, Helen Elwell, Veronique Filippi, Kelly Pickerill, Rachel Craik, Joel Singer, Rosemary Townsend, Hannah Blencowe, Eleni Z. Tsigas, Jeffrey N. Bone, Peter von Dadelszen, Laura A. Magee, the PRECISE Network, Umberto D’Alessandro, Anna Roca, Hawanatu Jah, Andrew Prentice, Melisa Martinez‐Alvarez, Brahima Diallo, Abdul Sesay, Sambou Suso, Baboucarr Njie, Fatima Touray, Yahaya Idris, Fatoumata Kongira, Modou F. S. Ndure, Lawrence Gibba, Abdoulie Bah, Yorro Bah, Marleen Temmerman, Angela Koech, Patricia Okiro, Geoffrey Omuse, Grace Mwashigadi, Mary Goretti Amondi, Consolata Juma, Joseph Mutunga, Moses Mukhanya, Robin Okello, Onesmus Wanje, Isaac Mwaniki, Marvin Ochieng, Emily Mwadime, Esperança Sevene, Corssino Tchavana, Salesio Macuacua, Anifa Vala, Helena Boene, Lazaro Quimice, Sonia Maculuve, Inacio Mandomando, Peter von Dadelszen, Laura A. Magee, Rachel Craik, Marie‐Laure Volvert, Hiten Mistry, Thomas Mendy, Donna Russell, Prestige Tatenda Makanga, Liberty Makacha, Reason Mlambo, Lucilla Poston, Rachel Tribe, Sophie Moore, Tatiana Salisbury, Aris Papageorghiou, Alison Noble, Rachel Craik, Hannah Blencowe, Veronique Filippi, Joy Lawn, Matt Silver, Joseph Akuze, Ursula Gazeley, Judith Cartwright, Guy Whitley, Sanjeev Krishna, Marianne Vidler, Jing Li, Jeff Bone, Mai‐Lei Woo Kinshella, Domena Tu, Ash Sandhu, Kelly Pickerill, Carla Carillho, Benjamin Barratt   +89 more
wiley   +1 more source

Predictive Value of Microalbuminuria, Systolic Blood Pressure, and Serum Uric Acid Levels for Preeclampsia/Severe Preeclampsia in Gestational Hypertensive Patients

Clinical and Experimental Obstetrics & Gynecology
Background: Preeclampsia is one of the most prevalent hypertensive disorders during pregnancy, leading to various issues that have an adverse impact on both the mother and the fetus.
Ha Hong Nguyen, Le Thi Nguyen, Phuc Hoang Tran, Kien Trung Nguyen, An Viet Tran, Son Kim Tran, Chau Minh Tran, Toan Hoang Ngo   +7 more
doaj   +1 more source

Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.

New England Journal of Medicine, 2006
BACKGROUND Alterations in circulating soluble fms-like tyrosine kinase 1 (sFlt1), an antiangiogenic protein, and placental growth factor (PlGF), a proangiogenic protein, appear to be involved in the pathogenesis of preeclampsia.
R. Levine, C. Lam, Cong Qian, Kai-fun Yu, S. Maynard, B. Sachs, B. Sibai, F. Epstein, Roberto Romero, R. Romero, R. Thadhani, S. Karumanchi   +11 more
semanticscholar   +1 more source

Neutrophil‐To‐Lymphocyte Ratio and Delivery Within 24 h in Preterm Premature Rupture of Membranes: A Retrospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the association between maternal neutrophil‐to‐lymphocyte ratio (NLR) and delivery within 24 h in women with preterm premature rupture of membranes (PPROM). Study Design and Setting Retrospective cohort study in a single university‐affiliated tertiary medical centre.
Daniel Gabbai, Itamar Gilboa, Anat Lavie, Yariv Yogev, Emmanuel Attali   +4 more
wiley   +1 more source

Association between maternal ABO blood group and preeclampsia: a prospective cohort study

Therapeutic Advances in Reproductive Health
Background: Preeclampsia is a leading cause of maternal morbidity and mortality. Various predictive methods exist, but none are without flaws. Risk factors vary in different women and at different gestational ages; hence, investigating non-modifiable ...
Zebulon C. Okechukwu, George U. Eleje, Joseph I. Adinma, Gerald O. Udigwe, Innocent I. Mbachu, Chukwuemeka O. Ezeama, Nkiru N. Ezeama, Chukwudi A. Ogabido, Chukwunwendu F. Okeke, Chidinma C. Okafor, Stella C. Okechukwu, Chinedu L. Olisa, Chigozie G. Okafor   +12 more
doaj   +1 more source

Relationship between Age and Parity with Late Onset Severe Preeclampsia at PKU Muhammadiyah Surabaya Hospital

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya
Maternal and fetal mortality is 31.15% due to undetected preeclampsia leading to eclampsia. Pre-occurrence of eclampsia is often characterized by severe preeclampsia symptoms such as increased blood pressure, and proteinuria, furthermore, preeclampsia is
Ninuk Dwi Ariningtyas, Penta Assidiqi Iman, Laily Irfana, Muhammad Anas   +3 more
doaj   +1 more source