Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
On the priority vector associated with a fuzzy preference relation and a multiplicative preference relation. [PDF]
We propose two straightforward methods for deriving the priority vector associated with a fuzzy preference relation. Then, using transformations between multiplicative preference relations and fuzzy preference relations, we study the relationships ...
Matteo Brunelli, Michele Fedrizzi
core
Childbearing preferences and family issues in Europe: evidence from the Eurobarometer 2006 survey [PDF]
Maria Testa
openalex +1 more source
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Falsifying the “Goodness” of Nonmarket Goods with Revealed Preference [PDF]
Some assert that it is impossible to test preference restrictions against revealed preference. The “goodness” preference restriction simply assumes that one value of a nonmarket good is preferred over another other with any fixed commodity consumption ...
David G. Brown
core
Stated Preferences for Conservation Policies Under Uncertainty: Insights on the Effect of Individuals’ Risk Attitudes in the Environmental Domain [PDF]
Michela Faccioli +2 more
openalex +1 more source
German GPs’ Self-Perceived Role in the COVID-19 Pandemic: Leadership, Participation in Regional Services and Preferences for Future Pandemic Preparedness [PDF]
Simon Kugai +6 more
openalex +1 more source
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Interactive group decision making procedure based on uncertain multiplicative linguistic preference relations [PDF]
Zeshui Xu
openalex +1 more source

