Results 51 to 60 of about 2,196,925 (223)

Preferences of patients with chronic obstructive pulmonary disease for online nursing consultation services: a discrete choice experiment

The Lancet Regional Health. Western Pacific
Background: Chronic obstructive pulmonary disease (COPD) imposes a significant burden on patients and society, and the majority of COPD patients in China manage their condition at home long-term but often fail to achieve the desired outcomes.
Juan He, Xiaoqian Xia, Jingbo Zhang, Niuniu Sun, Jiangfan Ma, Ping Yang, Chang Wu, Yang Ni, Yibo Wu   +8 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Barriers to sexual and reproductive health access among migrant women: a cross-sectional study in five regions in Morocco

BMJ Public Health
Introduction Morocco, a transit and destination country, has implemented policies granting free primary care and community outreach to improve sexual and reproductive health (SRH) services for migrant women.
Oumnia Bouaddi, Saad Zbiri, Kenza Hassouni, Mohamed Khalis, Jamila Mendili, Hafida Yartaoui, Sanaa Belabbes, Asmae Khattabi, Hanane Rassimi, Abdelilah El Marnissi, Abdelhakim Yahyane, Radouane Belaouali   +11 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Challenges and advantages of electronic prescribing system: a survey study and thematic analysis

BMC Health Services Research
Introduction Electronic prescribing (e-prescribing) systems can bring many advantages and challenges. This system has been launched in Iran for more than two years. This study aimed to investigate the challenges and advantages of the e-prescribing system
Hamid Bouraghi, Behzad Imani, Abolfazl Saeedi, Ali Mohammadpour, Soheila Saeedi, Taleb Khodaveisi, Tooba Mehrabi   +6 more
doaj   +1 more source

Hospital Characteristics Associated with Certified EHR Adoption among US Psychiatric Hospitals

Risk Management and Healthcare Policy, 2020
Xuejun Hu, 1, 2 Haiyan Qu, 2 Shannon H Houser, 2 Huoliang Chen, 1 Jinming Zhou, 1 Min Yu 3 1Department of Health Services Administration, Air Force Medical University, Xi’an, People’s Republic of China; 2Department of Health Services ...
Hu X, Qu H, Houser SH, Chen H, Zhou J, Yu M   +5 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Feasibility, Preference, and Impact of a Rapid Multiplexed Point-of-Care Digital Innovation (AideSmart!) to Expedite Screening of Sexually Transmitted Blood-Borne Infections in At-Risk Populations in Canada: Cross-Sectional Study

Journal of Medical Internet Research
BackgroundWith the need to expedite the detection of multiple sexually transmitted blood-borne infections (STBBIs), there is an increased demand for digital innovations and tests that improve the efficiency of point-of-care ...
Angela Karellis, Duncan Webster, Jean Boulanger, Kate Harland, Paige Feltmate, Stefanie Materniak, Gabriel Daunais-Laurin, Christine Mesa, Olivia Vaikla, John Kim, Nitika Pant Pai   +10 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source