Results 121 to 130 of about 13,467,897 (338)

A transforming interpenetrating-phase cermet with high strength and energy dissipation capacity

open access: yesMaterials Research Letters
Cermets generally exhibit a trade-off between strength and energy dissipation capacity. By applying a dual design strategy combining bioinspired architecting and metastability engineering, we developed a transforming interpenetrating-phase cermet made ...
Shuangyue Jia   +6 more
doaj   +1 more source

Mechanical and analytical screening of braided composites for transport fuselage applications [PDF]

open access: yes
The mechanics of materials progress in support of the goal of understanding the application of braided composites in a transport aircraft fuselage are summarized. Composites consisting of both 2-D and 3-D braid patterns are investigated.
Fedro, Mark J.   +2 more
core   +1 more source

Robust and Thermally Stable Silicone Aerogels with Hyperconnected Network via Kinetically Optimized Hyperbranched Silane Precursors

open access: yesAdvanced Science, EarlyView.
Reactivity‐Programmed Assembly: A kinetic‐control strategy is reported for constructing hyperconnected silicone aerogels with a robust “thick‐neck” architecture. By exploiting the reactivity disparity of precursors, flexible segments are uniformly embedded within a rigid skeleton.
Aoqing Yan   +9 more
wiley   +1 more source

Enhancing density and geometric accuracy in multi-material AlSi10Mg-Cu parts by combining laser powder bed fusion and field-assisted sintering technology

open access: yesMaterials & Design
Multi-material manufacturing enables the strategic placement of functional or costly materials only where necessary, enhancing both performance and resource efficiency, without the need for additional assembly operations.
Marco Bernet   +2 more
doaj   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

open access: yesAdvanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng   +5 more
wiley   +1 more source

Optimization and experimental validation of reinforcing fibers winding pattern for carbon/carbon composite crucible preform

open access: yesJournal of Industrial Textiles
In order to address the problem of transition slip between the cylindrical segment and the ellipsoidal head segment of the carbon/carbon composite crucible preform with asymmetrical structure during the winding process, a winding pattern combining ...
Jiuzhi Dong   +3 more
doaj   +1 more source

Reliability-Based Design Optimization of Bearing Hub Preform for Minimizing Defects Considering Manufacturing Tolerance in Hot Forging Process

open access: yesApplied Sciences
A study on the optimal design of preforms has previously been actively conducted as a method to solve defects such as voids and flash in forged products. However, previous research has generally been performed through deterministic optimization for ideal
Minseong Oh   +5 more
doaj   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang   +9 more
wiley   +1 more source

OPTIMASI PROSES MESIN STRETCH BLOW MOULDING PADA BOTOL 600 ML DENGAN METODE RSM (RESPONSE SURFACE METHODOLOGY) STUDI KASUS DI PT. UNIPLASTINDO INTERBUANA

open access: yesMedia Mesin, 2017
Pada proses produksi Aqua botol plastik 600 ml menggunakan mesin stretch blow moulding dengan sistem pneumatik, Pembuatan produk dengan menggunakan mesin ini memiliki faktor-faktor yang dapat mempengaruhi kualitas botol yang dihasilkan .
Mochamad Mas'ud
doaj  

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