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The Neuropsychology of the Prefrontal Cortex
Archives of Neurology, 1993Single photon emission computed tomography with the xenon inhalation technique is used to compare activation of regional cerebral blood flow in frontal brain regions during the performance of four widely used neuropsychological tests: the Continuous Performance Test, the Wisconsin Card Sorting Test, the Tower of London, and Porteus Mazes.
Nancy C. Andreasen +5 more
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Social Cognition and the Prefrontal Cortex [PDF]
Behavioral and Cognitive Neuroscience Reviews, 2003 Social cognitive neuroscience is a rapidly emerging field that utilizes cognitive neuroscientific techniques (e.g., lesion studies, neuroimaging) to address concepts traditionally in the social psychological realm (e.g., attitudes, stereotypes). The purpose of this article is to review published neuroscientific and neuropsychological research into ...
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, 1998 At this point in the description of this conceptual theory of higher-level brain function, one must ask a very important question: what new functional capabilities evolved with the creation of the limbic system level? The answer would be quite clear. The system acquired the ability to actively learn and perform discrete multistep control by utilizing ...
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The Prefrontal 'Cortex' in the Pigeon
Brain, Behavior and Evolution, 1982In 3 pigeons ablation of the posterodorsolateral neostriatum impaired delayed alternation without affecting visual discrimination. In mammals the same selective deficit is produced by lesions in the prefrontal system. The presently ablated neostriatal region resembles the mammalian prefrontal cortex also by being richly innervated with dopaminergic ...
Mogensen, Jesper, Divac, Ivan
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Plasticity and Memory in the Prefrontal Cortex
Reviews in the Neurosciences, 2008Neuropsychological and neuroimaging studies in humans have shown that the prefrontal cortex (PFC) is involved in long-term memory functioning. In general, the participation of the PFC in long-term memory has been attributed to its role in executive control rather than information storage.
Jung, MW Jung, Min Whan +4 more
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2010
The prefrontal cortex (PFC) circuits are characterized by several distinct features. First, the input–output connections of a PFC circuit with the rest of the brain are extraordinarily extensive. In the primates, pyramidal neurons in PFC are greatly more spinous than in the primary sensory areas, so they have a much larger capacity for synaptic ...
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The prefrontal cortex (PFC) circuits are characterized by several distinct features. First, the input–output connections of a PFC circuit with the rest of the brain are extraordinarily extensive. In the primates, pyramidal neurons in PFC are greatly more spinous than in the primary sensory areas, so they have a much larger capacity for synaptic ...
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Fables of the prefrontal cortex
Behavioral and Brain Sciences, 1995AbstractOn the basis of neuroiinaging studies, Posner & Raichle summarily report that the prefrontal cortex is involved in executive functioning and attention. In contrast to that superficial view, we briefly describe a testable model of the kinds of representations that are stored in prefrontal cortex, which, when activated, are expressed via ...
Arnaud Partiot +2 more
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2012
Publisher Summary Transgenic mouse models hold promise for elucidating the genetic basis of human pathophysiological conditions including addiction, schizophrenia, and dementia. These disorders typically involve changes in the regulation of emotion, behavioral flexibility, working memory, and decision making, behaviors that are critically dependent on
Yogita Chudasama, Keith B.J. Franklin
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Publisher Summary Transgenic mouse models hold promise for elucidating the genetic basis of human pathophysiological conditions including addiction, schizophrenia, and dementia. These disorders typically involve changes in the regulation of emotion, behavioral flexibility, working memory, and decision making, behaviors that are critically dependent on
Yogita Chudasama, Keith B.J. Franklin
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Dopamine, the prefrontal cortex and schizophrenia
Journal of Psychopharmacology, 1997Dysfunction of the prefrontal cortex (PFC) in schizophrenia has been suspected based on observations from clinical, neuropsychological and neuroimaging studies. Since the PFC receives a dense dopaminergic innervation, abnormalities of the mesocortical dopamine system have been proposed to contribute to the pathophysiology of schizophrenia.
Michael B. Knable, Daniel R. Weinberger
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Behavioral planning in the prefrontal cortex
Current Opinion in Neurobiology, 2001Recent studies have presented evidence that the prefrontal cortex plays a crucial role in every aspect of the cognitive processes necessary for behavioral planning: processing and integration of perceived or memorized information, associative learning, reward-based behavioral control, behavioral selection/decision-making and behavioral guidance.
Eiji Hoshi, Jun Tanji
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