Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen+12 more
wiley +1 more source
HUBUNGAN ANTARA TERJADINYA KEHAMILAN EKTOPIK DENGAN PENGGUNAAN KONTRASEPSI IUD DI BRSD JOMBANG PERIODE JANUARI 2008 – DESEMBER 2008 [PDF]
Background: Ectopic pregnancy have higher death risk than incidence of vaginal birth or abortion induction, so the succeed of pregnancys for the next pregnancies will be decreased in woman with ectopic pregnancies.
SHOLIHAH, HIDAYATUS
core
ABSTRACT Prader‐Willi syndrome (PWS) is a neurodevelopmental disorder typically caused by large deletions or imprinting defects on chromosome 15q11.2, encompassing multiple genes. While the contribution of individual genes to the PWS phenotype remains unclear, previous studies suggested that isolated deletions of MAGEL2, NDN, and MKRN3, excluding the ...
Jannis Buecking+6 more
wiley +1 more source
Ultrasound diagnosis and management of ectopic pregnancy [PDF]
Ectopic pregnancy is defined as the presence of a gestational sac outside the uterine cavity and has a prevalence of approximately 2%. Ninety-five percent of ectopic pregnancies occur in the non-interstitial portion of the fallopian tube (infundibulum ...
Vassallo, Pierre
core
Development of the occipitopetrosal junctions: A histological study using human fetuses
Abstract The temporal bone petrosa is connected to the occipital bone at two sites: one junction with the basilar part (medial junction) and another with the lateral part (lateral junction). Using histological specimens from 45 human fetuses (approximately 7–39 weeks of gestational age or GA), we aimed to describe possible changes in histology and ...
Ai Hirano‐Kawamoto+6 more
wiley +1 more source
Recurrent ectopic pregnancy in the fallopian tubes [PDF]
Here, we present a case with several episodes of ectopic pregnancy in the fallopian tubes, which was treated by medical and surgical methods, and followed for two years until it ended in a term successful ...
Besharat, M., Tabandeh, A.
core
PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah+2 more
wiley +1 more source
Cervical Ectopic Pregnancy [PDF]
[West J Emerg Med. 2012;13(1):125–126.]
Heer, Jag S.+2 more
openaire +5 more sources
Effect of interpregnancy interval on outcomes of pregnancy after miscarriage : retrospective analysis of hospital episode statistics in Scotland [PDF]
Peer reviewedPublisher ...
Bhattacharya, Siladitya+3 more
core +2 more sources