Results 171 to 180 of about 7,313,622 (355)

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

Advanced Science, EarlyView.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye, Anning Zhao, Xia Li, Yanqing Hao, Dong Huang, Jianmin Chen, Tiantian Li, Yangyang Dai, Wenchao Sun, Lie Ma, Songying Zhang, Liaobing Xin   +11 more
wiley   +1 more source

Disease course after pregnancy in women with progressive multiple sclerosis symptoms. [PDF]

Mult Scler
Shipley J, Beadnall HN, Sanfilippo PG, Horakova D, Boz C, Prat A, Ozakbas S, Kalincik T, Roos I, Altintas A, Eichau S, Skibina O, Alroughani R, Patti F, Etemadifar M, Lugaresi A, Tomassini V, Butzkueven H, van der Walt A, Jokubaitis VG.   +19 more
europepmc   +1 more source

Cell Fate Determination and Lineage Tracing: Technological Evolution and Multidimensional Applications

Advanced Science, EarlyView.
This figure is a candidate for the cover image. It shows a whole‐mount fluorescent image of lymphatic vessels (red) in the heart of an adult Cdh5‐Dre; Prox1‐RSR‐CreER; Rosa26‐tdT mouse. Image courtesy of Ximeng Han. Abstract Cell fate determination is a fundamental process in multicellular development.
Hui Chen, Zhicong Liu, Qiang Shu, Bin Zhou   +3 more
wiley   +1 more source

Multimorbidity before, during and after pregnancy among women in low-income and middle-income countries: protocol for a scoping review. [PDF]

BMJ Open
Ramokolo V, Roomaney RA, Maqungo M, Nyirenda M, Puri P, Yakubu K, Gummidi B, Zembe-Mkabile W, Xu X, McCauley M.   +9 more
europepmc   +1 more source

Pathways of the determinants of unfavourable birth outcomes in Kenya

, 2003
This paper explores the pathways of the determinants of unfavourable birth outcomes, such as premature birth, the size of the baby at birth, and Caesarean section deliveries in Kenya, using graphical loglinear chain models. The results show that a number
Diamond, Ian, Madise, Nyovani, Magadi, Monica, Smith, Peter   +3 more
core  

H3K27ac Is Essential for Human Naive Pluripotency Modulated by m6A‐Driven EP300 Expression

Advanced Science, EarlyView.
An et al. reveal H3K27ac elevation is essential for establishing and maintaining human naive pluripotency; its inhibition disrupts this state while enhancement promotes it. METTL3‐mediated m6A modification indirectly controls H3K27ac by suppressing EP300 expression. Reduced EP300 lowers H3K27ac, impeding naive pluripotency.
Chenrui An, Ke Zhong, Xiangjin Kang, Yingying Zhang, Yudan Shang, Hao Liu, Yushan Ji, Jinbei Zeng, Jiajin Lin, Long Jin, Zelong Lin, Yang Yu, Xuetao Shi, Yong Fan   +13 more
wiley   +1 more source

High-Risk Pregnancy with Solid Pseudopapillary Tumor of the Pancreas Complicated by Obstetric Antiphospholipid Syndrome: A Case Report. [PDF]

Int J Womens Health
Li S, Yu S, Yu X, Meng X, Zhu Y.
europepmc   +1 more source

Big Data and AI‐Powered Modeling: A Pathway to Sustainable Precision Animal Nutrition

Advanced Science, EarlyView.
This review summarizes the current landscape of big data and AI‐powered modeling in animal nutrition, covering techniques including intelligent data acquisition, data augmentation, explainable machine learning, heuristic algorithms, and life cycle assessment‐based sustainability evaluation.
Shuai Zhang, Changhua Lai, Jinbiao Zhao, Junjun Wang   +3 more
wiley   +1 more source

IVF and pregnancy outcomes: the triumphs, challenges, and unanswered questions. [PDF]

J Ovarian Res
Bentov Y, Schenker J.
europepmc   +1 more source

Family planning:fertility and parenting ideals in urban adolescents [PDF]

, 2015
Chipman, Abigail, Morrison, Edward
core   +2 more sources