Results 71 to 80 of about 81,186 (261)

Hepcidin and iron homeostasis during pregnancy. [PDF]

, 2014
Hepcidin is the master regulator of systemic iron bioavailability in humans. This review examines primary research articles that assessed hepcidin during pregnancy and postpartum and report its relationship to maternal and infant iron status and birth ...
Cadwell, Brooke, Day, Jessica, Koenig, Mary Dawn, Nemeth, Elizabeta, Tussing-Humphreys, Lisa   +4 more
core   +1 more source

Translation of a physiologically‐based pharmacokinetic model for dabigatran etexilate to the design of a safety and efficacy study in post‐partum women

British Journal of Clinical Pharmacology, EarlyView.
Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro, Lorna Aucott, Farhad Kamali, Paul Ayuk   +3 more
wiley   +1 more source

Establishment of a latex immunochromatography for detecting bovine early pregnancy-related glycoproteins

Applied Microbiology and Biotechnology
Early pregnancy diagnosis in dairy cows is an important part of the production processes. Accurate early pregnancy diagnosis can help veterinarians identify open cow as soon as possible and carry out the second breeding earlier, which is of great ...
Linlin Gu, Weiwei Wang, Mingjie Yang, Yafang Yu, Hui Chen, Kang Zhang, Kehu Yuan, Hui Fu, Qiuhua Mo, Bo Yang   +9 more
doaj   +1 more source

Effect of Human Chorionic Gonadotropin Injection on Some of Reproductive Parameters in Local Iraqi Ewes

مجلة الانبار للعلوم البيطرية
Aims and Objectives: Evaluate the effect of hCG injection on some of the reproductive parameters in local Iraqi ewes during the breeding season. Materials and Methods: Thirty seven ewes with an average age of 2–4 years were studied, along with sexually ...
Mazin Khalid Mahmood,, Yassen Taha Abdul‑Rahaman   +1 more
doaj   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Does Subcutaneous Administration of Granulocyte Colony Stimulating Factor Improve Pregnancy Outcome in Patients Undergoing Intracytoplasmic Sperm Injection? [PDF]

Journal of Kerman University of Medical Sciences, 2019
Background:Expression of granulocyte colony stimulating factor (G-CSF) and its receptors in embryo and endometrium implicates the involvement of this glycoprotein on implantation process.
Roya Kabodmehri, Marzieh Mehrafza, Tahereh Zare Yousefi, Sahar Saghati Jalali, Fatemeh Sedaghat, Elmira Hosseinzadeh, Azadeh Raoufi, Sajedeh Samadnia, Zahra Nikpouri   +8 more
doaj   +1 more source

Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis [PDF]

, 2018
Indexación: Scopus.Hypothyroxinemia (Hpx) is a thyroid hormone deficiency (THD) condition highly frequent during pregnancy, which although asymptomatic for the mother, it can impair the cognitive function of the offspring.
Albornoz, E., Binzberger, R., Bueno, S.M., Bugueño, K., Cabello-Verrugio, C., Elorza, A.A., Haensgen, H., Jara Fernández, E.L., Kalergis, A.M., Opazo, M.C., Riedel, C.A., Rivero-Castillo, T., Simon, F., Venegas Salas, L.F.   +13 more
core   +2 more sources

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy. [PDF]

, 2011
Our study shows that in Indonesian cancer patients treated with highly cytostatic emetogenic, carriership of the CTG haplotype of the ABCB1 gene is related to an increased risk of delayed chemotherapy-induced nausea and ...
Baak-Pablo, Renee F, Gelderblom, Hans, Guchelaar, Henk-Jan, Hakimi, Mohammad, Mustofa, Mustofa, Nortier, Johann W R, Perwitasari, Dyah A, van der Straaten, Robert J H M, Wessels, Judith A M   +8 more
core   +2 more sources