Results 101 to 110 of about 80,544 (257)

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Maternal and infant gut microbiome

iMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

A study on structural changes of placenta in pregnancy induced hypertensive pregnancies in eastern India [PDF]

Al Ameen Journal of Medical Sciences
Background: Complications of pregnancy are reflected in placenta. Placenta is the mirror of maternal and foetal status. So a study of placenta and new born will help to identify the disease by which mother is affected in pregnancies of pregnancy induced ...
Biswanath Baskey, Ratnadeep Poddar, Iman Sinha, Joydip Saha, Akash Kusum Banerjee   +4 more
doaj  

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Optimizing Expectations Leads to Enhanced Efficacy of a Mindfulness‐Based Intervention in Individuals With Low‐Baseline Expectations: A Randomized Controlled Trial

Journal of Clinical Psychology, EarlyView.
ABSTRACT Introduction Treatment expectations for medical and psychological treatments and positive patient‐provider interactions are critical mechanisms driving the placebo effect and may augment an intervention's effects. However, it remains unclear whether optimizing treatment expectations is beneficial for all individuals.
Stefan Salzmann, Frank Euteneuer, Christiane A. Melzig, Winfried Rief, Christoph Benke   +4 more
wiley   +1 more source

CIRCULATING VISFATIN LEVEL AND ITS ASSOCIATION WITH LIPID BIOMARKERS IN PREGNANCY INDUCED HYPERTENSION

Gomal Journal of Medical Sciences, 2017
Background: Hypertensive disorder in pregnancy is a major disorder that affects the fetal and maternal prognosis. A newer adipokine, visfatin has been related in the pathogenesis of pregnancy induced hypertension.
Asmat Shaheen, Salim Khattak, Zahoor Ahmed, Musarrat Jabeen, Rubina Nazli, Roshan Ali   +5 more
doaj  

Discrete components of stress impact trajectories of childhood irritability but not adolescent mental health outcomes

JCPP Advances, EarlyView.
Thick red line indicates positive mixture effect of stressors predicting high irritability class. Maternal demoralization, material hardship, maternal perceived stress, and intimate partner violence contributed to the mixture effect (thick borders on boxes).
Mariah DeSerisy, Huiyu Yang, Jacob W. Cohen, David Pagliaccio, Julie B. Herbstman, Bradley S. Peterson, Frederica P. Perera, Virginia Rauh, Amy E. Margolis   +8 more
wiley   +1 more source

Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Xenon MRI is increasingly used to evaluate patients with interstitial lung disease (ILD) and pulmonary hypertension (PH), both of which are common manifestations of systemic sclerosis (SSc). As such, Xe‐MRI may be suited to interrogate lung function impairment in SSc.
Dawson Shaver, Steven Haworth, Evan Graumann, Bradie Frizzell, David H. Lee, Jiwoong Choi, Chase S. Hall, Scott M. Matson, Mark Hamblin, Mario Castro, Paul S. Schmidt, Peter J. Niedbalski   +11 more
wiley   +1 more source

CLINICAL AND IMMUNOLOGICAL COURSE OF GESTATION DURING PREGNANCY INDUCED HYPERTENSION

Акушерство, гинекология и репродукция, 2016
The aim of this research was studies character of clinical course of gestation and immunological markers in pregnant women with gestational hypertension and pre-eclampsia.
N. A. Shakhbazova
doaj