Results 141 to 150 of about 2,406,534 (370)

Decision Making with Machine Learning and ROC Curves [PDF]

open access: yesarXiv, 2019
The Receiver Operating Characteristic (ROC) curve is a representation of the statistical information discovered in binary classification problems and is a key concept in machine learning and data science. This paper studies the statistical properties of ROC curves and its implication on model selection.
arxiv  

Advice from the Field: Youth Employment Programs and Unintended Pregnancy [PDF]

open access: yes, 2003
This report further explores the connection between the fields of pregnancy prevention and youth employment. It provides "advice from the field" from five youth employment providers about their efforts to combat unintended pregnancy and to provide family
Christine Grisham
core  

Analysis of the Longitudinal Behavior of Serum Levels of Soluble Flt1 and Placental Growth Factor in Pregnant Patients With Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective This study analyzed longitudinal trajectories of soluble Flt1 (sFlt1) levels, placenta growth factor (PlGF) levels, and sFlt1:PlGF ratios in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14–18, 24–26, 30–32, 34–36, and 38–40 weeks), stored at −80°C, and evaluated for serum levels ...
Nilson R. de Jesús   +7 more
wiley   +1 more source

Bias in studies of prenatal exposures using real-world data due to pregnancy identification method [PDF]

open access: yesarXiv
Background: Researchers typically identify pregnancies in healthcare data based on observed outcomes (e.g., delivery). This outcome-based approach misses pregnancies that received prenatal care but whose outcomes were not recorded (e.g., at-home miscarriage), potentially inducing selection bias in effect estimates for prenatal exposures. Alternatively,
arxiv  

Chronic stress may disrupt covariant fluctuations of vitamin D and cortisol plasma levels in pregnant sheep during the last trimester: a preliminary report [PDF]

open access: yesarXiv, 2019
Psychosocial stress during pregnancy is a known contributor to preterm birth, but also has been increasingly appreciated as an in utero insult acting long-term on prenatal and postnatal neurodevelopmental trajectories. These events impact many information molecules, including both vitamin D and cortisol.
arxiv  

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

open access: yesAdvanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang   +6 more
wiley   +1 more source

Involving Knowledge Users in Health Services Research: Collective Reflections and Learning From a National Evaluation of Recurrent Miscarriage Services

open access: yesHealth Expectations
Introduction Involving knowledge users in research can facilitate the translation of evidence into policy and practice. How to best involve and support various types of knowledge users, including patient and public involvement contributors, in research ...
Marita Hennessy   +4 more
doaj   +1 more source

Placental Vitamin D-Binding Protein Expression in Human Idiopathic Fetal Growth Restriction

open access: yesJournal of Pregnancy, 2017
Vitamin D-binding protein is a multifunctional serum protein with multiple actions related to normal health. Vitamin D-binding protein transports vitamin D and influences the metabolism of this key hormone but it also has additional immunomodulatory and ...
Alice F. Wookey   +6 more
doaj   +1 more source

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