Results 181 to 190 of about 1,360,076 (317)

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Ruptured Ovarian Ectopic Pregnancy Managed Laparoscopically With Subsequent Term Delivery After 2 years Follow-Up: A Case Report and Literature Review

Case Reports in Obstetrics and Gynecology
Elizabeth Bajomo, Asma Aziz, Mona Sharma
doaj   +1 more source

Expectations predict early pregnancy-related symptom burden. [PDF]

Sci Rep
Shedden-Mora M, Schymanski V, Albers R, Beth B, Garthus-Niegel S, Crum AJ, Autzen L.   +6 more
europepmc   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Validation of pregnancy date estimation from outpatient electronic health record data. [PDF]

JAMIA Open
Lyon-Scott K, Dankovchik J, Donovan J, Hauschildt J, Vesco KK, Boone-Heinonen J, Schmidt T.   +6 more
europepmc   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Patients' Experiences With Pregnancy of Unknown Location: A Qualitative Study. [PDF]

J Patient Exp
Ifthikhar R, Schueler KE, Mody SK.
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Spontaneous rupture and massive hemoperitoneum from uterine leiomyomas and adenomyosis in a nongravid and unscarred uterus

Taiwanese Journal of Obstetrics & Gynecology, 2015
Cheng-Ran Peng, Chie-Pein Chen, Kuo-Gon Wang, Liang-Kai Wang, Yi-Yung Chen, Chen-Yu Chen   +5 more
doaj   +1 more source

Maternal and Neonatal Outcomes of Immune Thrombocytopenia in Pregnancy: A Five-Year Single-Center Cross-Sectional Study. [PDF]

Health Sci Rep
Elkorashi S, Magboul H, Al-Mashdali AF, Alnajjar M, AlMallahi N, Abdalla E, Soliman DS, Aldali S, Elsheikh M, Cherif H, Mohamed SF.   +10 more
europepmc   +1 more source