Results 231 to 240 of about 2,632,772 (344)

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Trimester-Specific Impacts of Steatotic Liver Disease on Adverse Pregnancy Outcomes: A Retrospective Cohort Study. [PDF]

Liver Int
Yang L, Yang S, Wang Y, Hebestreit A, Wang M, Yang Y, Wu Y, Long Y, Wang H.   +8 more
europepmc   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

Incidence of Pregnancy after Initiation of Antiretroviral Therapy in South Africa: A Retrospective Clinical Cohort Analysis [PDF]

, 2012
Daniel Westreich, Mhairi Maskew, Dennis Rubel, Pippa Macdonald, Imogen Jaffray, Pappie Majuba   +5 more
openalex   +1 more source

Does the perceived neighborhood environment promote mental health during pregnancy? Confirmation of a pathway through social cohesion in two Spanish samples

, 2021
Mikel Subiza‐Pérez, Gonzalo García‐Baquero, Izaro Babarro, Asier Anabitarte, Xavier Delclòs‐Alió, Guillem Vich, Oriol Roig-Costa, Carme Miralles‐Guasch, Nerea Lertxundi, Jesús Ibarluzea   +9 more
openalex   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Insomnia symptoms increase during pregnancy, but no increase in sleepiness - Associations with symptoms of depression and anxiety

, 2020
Linda Aukia, E. Juulia Paavonen, Tuire Jänkälä, Mimmi Tolvanen, Riikka Korja, Linnéa Karlsson, Hasse Karlsson, Päivi Polo‐Kantola   +7 more
openalex   +2 more sources

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Myomectomy During Pregnancy: Decision-Making and Outcomes-A Report of 2 Cases. [PDF]

Clin Med Insights Case Rep
Igwemadu GT, Nnochiri A, Sharma M.
europepmc   +1 more source

Caffeine consumption during early pregnancy impairs oviductal embryo transport, embryonic development and uterine receptivity in mice† [PDF]

, 2018
Jingjing Qian, Yunfang Zhang, Yongcun Qu, Liwen Zhang, Junchao Shi, Xudong Zhang, Shichao Liu, Bo Hyun Kim, Sung Jin Hwang, Tong Zhou, Qi Chen, Sean M. Ward, Enkui Duan, Ying Zhang   +13 more
openalex   +1 more source