Results 261 to 270 of about 2,136,997 (319)

The E3 Ubiquitin Ligase ARIH1 Facilitates Colorectal Cancer Progression by Promoting Oxidative Phosphorylation via the Mitochondrial Translocation of K63‐Linked Ubiquitinated PHB1

Advanced Science, EarlyView.
The RBR E3 ubiquitin ligase ARIH1, which is upregulated in colorectal cancer cells, promotes cell growth and metastasis and correlates with an unfavorable CRC prognosis. Mechanistically, ARIH1 catalyzes K63‐linked ubiquitination of PHB1, enhancing the interaction between PHB1 and Akt.
Ying Tong, Zhenling Wang, Yong Wang, Yang Chen, Hongqiang Zhang, Yunfei Lu, Lei Xu, Hengyang Shen, Changzhi Huang, Min Zhao, Wenjie Li, Shuai Wang, Yu Shao, Zan Fu   +13 more
wiley   +1 more source

Association of premarital pregnancy with adverse birth outcomes and its characteristics in Japan. [PDF]

Contracept Reprod Med
Okui T, Nakashima N.
europepmc   +1 more source

ESTROGEN METABOLISM IN HUMAN PREGNANCY; A STUDY WITH THE AID OF DEUTERIUM

, 1954
W.H. Pearlman, M.R.J. Pearlman, A.E. Rakoff   +2 more
openalex   +1 more source

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

Advanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li, Huihui Yu, Ruixian Tian, Xingxing Wang, Ting Xing, Chenyi Xu, Tengteng Li, Xue Du, Qianqian Cui, Biao Yu, Yunxia Cao, Zongzhi Yin   +11 more
wiley   +1 more source

Estimated effect of teenage pregnancy on adverse birth outcome in Sub-Saharan African countries: propensity score matching analysis of recent demographic and health survey data. [PDF]

BMC Pregnancy Childbirth
Teshale G, Dellie E, Aschalew AY, Tsehay CT, Worku N, Tafere TZ, Baykemagn ND, Hagos A.   +7 more
europepmc   +1 more source

IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex

Advanced Science, EarlyView.
This study reveals IFITM2 as a key regulator of endocytosis in radial glial cells (RGCs) during brain development. IFITM2's YXXø motif and phosphoinositide‐binding residues (K82/K87) are essential for endosome formation. IFITM2 deficiency disrupts the embryonic cortical neurogenesis, revealing a conserved mechanism linking endocytic dynamics to neural ...
Yuqing Lv, Wenzheng Zou, Lin Li, Shukui Zhang, Jiaqi Liang, Jiali Pu, Jianwei Jiao   +6 more
wiley   +1 more source

Comparison of pregnancy outcomes for high morphological scoring mosaic vs. low morphological scoring euploid embryos: a retrospective cohort study. [PDF]

J Ovarian Res
Geng T, Zhou Q, Wang Y, Ji H, Ding K, Zheng Z, Yang Y, Zhang J, Zhao C, Ling X.   +9 more
europepmc   +1 more source

AuCu@CuO2 Aerogels with H2O2/O2 Self‐Supplying and Quadruple Enzyme‐Like Activity for MRSA‐Infected Diabetic Wound Management

Advanced Science, EarlyView.
The AuCu@CuO2 aerogels demonstrate favorable photothermal properties, four types of enzyme‐like activities, and H2O2/O2 self‐supplying to modulate the complex microenvironment of MRSA‐infected diabetic wounds. The results indicate that the AuCu@CuO2 aerogel can be activated by the microenvironment of diabetic wound infection, alleviating inflammation ...
Xiaofeng Tan, Nanyun Lin, Sha Yang, Hongyu Gong, Minghui Wang, Na Li, Fen Liu, Dajun Rao, Yingying Wu, Jing Tang, Qinglai Yang   +10 more
wiley   +1 more source

ART to prevent vertical transmission in Latin America: where are we in the "Treat-All" era? [PDF]

J Int AIDS Soc
Castillo-Rozas G, Fonseca FF, Castilho J, Rebeiro PF, Machado DM, Luque MT, Jalil EM, Mejia F, Kim A, Shepherd BE, Cortes CP.   +10 more
europepmc   +1 more source

The Dynamic Landscape of 3′‐UTR Alternative Polyadenylation Across Mouse Fetal Development and Anatomy

Advanced Science, EarlyView.
This work maps 3′‐UTR APA across mouse fetal development and tissues, identifying conserved sequence determinants that influence pAS choice. In fetal brain tissues, complex APA dynamics during development are potentially regulated by RBPs like Rbm38, which restrict distal pAS usage.
Qin Wang, Xin Chen, Xiao‐Ou Zhang
wiley   +1 more source