Results 51 to 60 of about 2,658,279 (341)

Factors associated with crisis pregnancies in Ireland: Findings from three nationally representative sexual health surveys [PDF]

, 2015
Background: Findings on the demographic and sexual health characteristics associated with the experience of a crisis pregnancy is important to inform the public health policy of a country, including Ireland.
AO Tsui, AP Mohllajee, Ashling Bourke, BM Magnusson, Caroline Kelleher, Central Statistics Office, Central Statistics Office, D Cheng, Daniel Boduszek, DG Foster, F Kreuter, F Lakha, H Tolonen, IBM Corp, J Murphy-Lawless, JB Homco, JJ Speidel, K Kaye, K Rundle, Karen Morgan, L Lindberg, LB Finer, LB Finer, M Nic Ghiolla Phádraig, MA Biggs, MR Frankel, O McBride, Organisation for Economic Co-operation and Development, PK Kohler, PS Shah, R Layte, R Layte, RK Jones, RK Jones, SK Henshaw, TE Mueller, WD Mosher   +36 more
core   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

OX40 (CD134) Expression on T Regulatory Cells Is Related to Serious Hypertensive Disorders in Pregnancy

Journal of Cardiovascular Development and Disease, 2023
Hypertension is one of the leading causes of morbidity and mortality among women related to pregnancy, childbirth and the postpartum period. The pathogenesis of gestational hypertension is complex and still not fully understood. The aim of this study was
Maciej Kwiatek, Agnieszka Kojak, Anna Kwaśniewska   +2 more
doaj   +1 more source

Maternal haemoglobin concentrations before and during pregnancy and stillbirth risk: A population-based case-control study [PDF]

, 2016
Background: Results of previous studies on the association between maternal haemoglobin concentration during pregnancy and stillbirth risk are inconclusive. It is not clear if haemoglobin concentration before pregnancy has a role.
Aarabi, M., Bahmanyar, S., Cnattingius, S., Maghsoudlou, S., Montgomery, S.M., Semnani, S., Stephansson, O.   +6 more
core  

Psychometric Evaluation of an Instrument to Measure Prospective Pregnancy Preferences: The Desire to Avoid Pregnancy Scale. [PDF]

, 2019
BACKGROUND:Existing approaches to measuring women's pregnancy intentions suffer important limitations, including retrospective assessment, overly simple categories, and a presumption that all women plan pregnancies. No psychometrically valid scales exist
Foster, Diana G, Gould, Heather, Ralph, Lauren J, Rocca, Corinne H, Wilson, Mark   +4 more
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Neonatal outcomes in the surgical management of placenta accreta spectrum disorders: a retrospective single-center observational study from 468 Vietnamese pregnancies beyond 28 weeks of gestation

BMC Pregnancy and Childbirth
Background Placenta accreta spectrum disorders (PASDs) increase the mortality rate for mothers and newborns over a decade. Thus, the purpose of the study is to evaluate the neonatal outcomes in emergency cesarean section (CS) and planned surgery as well ...
Phuc Nhon Nguyen, Anh Dinh Bao Vuong, Xuan Trang Thi Pham   +2 more
doaj   +1 more source

Different Gestational Diabetes Phenotypes: Which Insulin Regimen Fits Better?

Frontiers in Endocrinology, 2021
ObjectiveMaternal characteristics and OGTT values of pregnancies complicated by gestational diabetes mellitus (GDM) were evaluated according to treatment strategies.
Federico Mecacci, Federico Mecacci, Federica Lisi, Silvia Vannuccini, Silvia Vannuccini, Serena Ottanelli, Marianna Pina Rambaldi, Caterina Serena, Serena Simeone, Felice Petraglia   +9 more
doaj   +1 more source

Increasing uptake of influenza vaccine by pregnant women post H1N1 pandemic: a longitudinal study in Melbourne, Australia, 2010 to 2014 [PDF]

, 2015
Background: A Melbourne (Australia) university affiliated, tertiary obstetric hospital provides lay and professional education about influenza vaccine in pregnancy annually each March, early in the local influenza season.
McCarthy, Elizabeth Anne, McDonald, Susan, Pollock, Wendy, Sommerville, Maree, Tapper, Lauren   +4 more
core   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source