Results 211 to 220 of about 1,141,140 (306)

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

open access: yesAdvanced Science, EarlyView.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao   +4 more
wiley   +1 more source

Experiences of Obstetrician-Gynecologists Providing Pregnancy Care After Dobbs.

open access: yesJAMA Netw Open
Cutler AS   +4 more
europepmc   +1 more source

Not all Medicaid for pregnancy care is delivered equally. [PDF]

open access: yesPLoS One
Swartz JJ, Kaufman M, Rodriguez MI.
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

open access: yesAdvanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang   +13 more
wiley   +1 more source

Record‐High Latent Heat, Ultra‐Fast Relaxation and Closed‐Loop Recycling Double‐Brush Polymer Networks for Self‐Adaptive Thermal Interface Management

open access: yesAdvanced Science, EarlyView.
By grafting dense long double‐brush chains, we synthesized bottlebrush networks with high theoretical enthalpy. Their low entanglement, combined with dynamic bonds, promotes crystalline domain reorganization and minimizes enthalpy loss, achieving a record enthalpy of 240.7 J·g−1.
Qiguang Liu   +7 more
wiley   +1 more source

PREgnancy Care Integrating translational Science, Everywhere (PRECISE): a prospective cohort study of African pregnant and non-pregnant women to investigate placental disorders - cohort profile. [PDF]

open access: yesBMJ Open
Craik R   +40 more
europepmc   +1 more source

Soft, Flexible, and Stretchable Platforms for Tissue‐Interfaced Bioelectronics

open access: yesAdvanced Science, EarlyView.
Bio‐integrated electronics provide mechanically compliant and stable interfaces with soft biological tissues. Representative applications include neural interfaces, wet‐organadhesive electronics, and skin‐interfaced devices. E represents Young´s modulus and ε represents strain.
Kento Yamagishi   +3 more
wiley   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

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