Results 91 to 100 of about 141,826 (241)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

The Benefits and Concerns of Veganism in Women\u27s Health [PDF]

open access: yes, 2017
There are many health benefits of consuming a vegan diet. It is associated with a decreased incidence of obesity, cardiovascular disease, type two diabetes, and a variety of cancers. Despite its numerous benefits, there are several concerns for consumers
Hester, Elisa R
core   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

A study of the pulmonary complications of preterm infants after prenatal corticosteroids prophylaxis in a major Bulgarian hospital [PDF]

open access: yes, 2019
: An increasingly common problem in obstetrics and neonatology is premature birth. This problem is the cause of many health complications in premature neonates and is leading to neonatal mortality.
Buttigieg, George G.   +3 more
core  

From Kitchen to Clinic: Integrating Food as a Vital Component of Healthcare

open access: yesFuture Postharvest and Food, EarlyView.
This review highlights how nutrition‐based interventions, such as medically tailored meals and personalized dietary strategies, can improve chronic disease management, reduce healthcare costs, and enhance patient outcomes. ABSTRACT The concept of food as medicine has garnered increasing attention as an integrative approach to prevent and manage chronic
Sanghee Han   +2 more
wiley   +1 more source

Physical activity and hypertension in South African adults [PDF]

open access: yes, 2014
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.5 South Africa LicenseEstimates suggest that approximately 6-million South Africans have hypertension, with half classified as stage 1 (mild).
Collard, Jade   +5 more
core  

Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets

open access: yesFood Safety and Health, EarlyView.
Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar   +5 more
wiley   +1 more source

Jefferson Digital Commons quarterly report: January-March 2020 [PDF]

open access: yes, 2020
This quarterly report includes: New Look for the Jefferson Digital Commons Articles COVID-19 Working Papers Educational Materials From the Archives Grand Rounds and Lectures JeffMD Scholarly Inquiry Abstracts Journals and Newsletters Master of Public ...
Copeland, LIBT, James   +2 more
core   +1 more source

Gout in pregnancy: Obstetric and neonatal outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar   +3 more
wiley   +1 more source

Childhood Type II Diabetes: The Risks and Complications [PDF]

open access: yes, 2015
Type II Diabetes Mellitus is an endocrine disorder that affects people of all ages. Type II Diabetes was once considered adult-onset diabetes, as it was nearly exclusively diagnosed in adults. Over the last three decades, the number of children diagnosed
Kapke, Danielle R
core   +1 more source

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