Results 121 to 130 of about 87,719 (216)

Safety of belimumab during pregnancy: associations with maternal and fetal or newborn adverse outcomes based on FAERS data. [PDF]

Ther Adv Drug Saf
Lin Y, Yao J.
europepmc   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Pregnancies in women with rare diseases: Selected maternal and perinatal outcomes. [PDF]

Acta Obstet Gynecol Scand
Kosian P, Niederhöfer K, Jost E, Gembruch U, Bender T, Grigull L, Merz WM.   +6 more
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Assisted Reproductive Technology and Cardiovascular Outcomes in Women: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Wei SQ, Li W, Auger N, Potter BJ, Paradis G, Healy-Profitós J, Tan SL.   +6 more
europepmc   +1 more source

Standardised Methods for Developing Conceptual Frameworks for Placental Disorders of Pregnancy: Pre‐Eclampsia and Stillbirth

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Risk factors for the placental disorders of pregnancy (pre‐eclampsia, fetal growth restriction, preterm birth, and stillbirth) are complex, frequently involving the interplay between clinical factors and wider social and environmental determinants of health.
Terteel Elawad, Mai‐Lei Woo Kinshella, Ellie Stokes, Kelly Pickerill, Elisa Dalle Piagge, Marianne Vidler, Ella Stanley, Marie‐Laure Volvert, Jeffrey N. Bone, Helen Elwell, Hiten D. Mistry, Violet Mateljan, Eleni Tsigas, Veronique Filippi, Peter von Dadelszen, Hannah Blencowe, Laura A. Magee, PRECISE Network   +17 more
wiley   +1 more source

Long-term cardiovascular risks in patients with hypertensive disorders of pregnancy treated with nifedipine or labetalol. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Aggarwal P, Derti S, Yannamani A, Newman JS, Tuli R, Dargan P, Indaram M, Kassis-George H.   +7 more
europepmc   +1 more source

Towards the Development of a Conceptual Framework of the Determinants of Pre‐eclampsia: A Hierarchical Systematic Review of Biomarkers

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Pre‐eclampsia is a leading cause of maternal and perinatal morbidity and mortality. There are several determinants of individual pregnant women's risk of developing pre‐eclampsia, including biomarkers and ultrasound markers. Objective A conceptual framework to collate and summarise the extensive body of literature on biomarkers ...
Terteel Elawad, Hiten D. Mistry, Mai‐Lei Woo Kinshella, Marianne Vidler, Marie‐Laure Volvert, Helen Elwell, Veronique Filippi, Kelly Pickerill, Rachel Craik, Joel Singer, Rosemary Townsend, Hannah Blencowe, Eleni Z. Tsigas, Jeffrey N. Bone, Peter von Dadelszen, Laura A. Magee, the PRECISE Network, Umberto D’Alessandro, Anna Roca, Hawanatu Jah, Andrew Prentice, Melisa Martinez‐Alvarez, Brahima Diallo, Abdul Sesay, Sambou Suso, Baboucarr Njie, Fatima Touray, Yahaya Idris, Fatoumata Kongira, Modou F. S. Ndure, Lawrence Gibba, Abdoulie Bah, Yorro Bah, Marleen Temmerman, Angela Koech, Patricia Okiro, Geoffrey Omuse, Grace Mwashigadi, Mary Goretti Amondi, Consolata Juma, Joseph Mutunga, Moses Mukhanya, Robin Okello, Onesmus Wanje, Isaac Mwaniki, Marvin Ochieng, Emily Mwadime, Esperança Sevene, Corssino Tchavana, Salesio Macuacua, Anifa Vala, Helena Boene, Lazaro Quimice, Sonia Maculuve, Inacio Mandomando, Peter von Dadelszen, Laura A. Magee, Rachel Craik, Marie‐Laure Volvert, Hiten Mistry, Thomas Mendy, Donna Russell, Prestige Tatenda Makanga, Liberty Makacha, Reason Mlambo, Lucilla Poston, Rachel Tribe, Sophie Moore, Tatiana Salisbury, Aris Papageorghiou, Alison Noble, Rachel Craik, Hannah Blencowe, Veronique Filippi, Joy Lawn, Matt Silver, Joseph Akuze, Ursula Gazeley, Judith Cartwright, Guy Whitley, Sanjeev Krishna, Marianne Vidler, Jing Li, Jeff Bone, Mai‐Lei Woo Kinshella, Domena Tu, Ash Sandhu, Kelly Pickerill, Carla Carillho, Benjamin Barratt   +89 more
wiley   +1 more source

A scoping review exploring women's experiences of cardiometabolic pregnancy complications and future cardiovascular health implications. [PDF]

NPJ Cardiovasc Health
Xu W, Wisnewski M, Kindsvater C, Teede H, Moran LJ, Lang S.   +5 more
europepmc   +1 more source