Results 161 to 170 of about 278,902 (273)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Sex Differences in Hypertension Risk: Insights from Placental Genomics and Pregnancy-Driven Vascular Programming. [PDF]

Int J Mol Sci
Moustakli E, Potiris A, Zikopoulos A, Mavrogianni D, Kathopoulis N, Drakaki E, Anagnostaki I, Tsakiridis I, Dagklis T, Skentou C, Drakakis P, Christopoulos P, Stavros S.   +12 more
europepmc   +1 more source

Identifying Potential Vulnerability to Long COVID Through Global‐to‐Local Inequalities in Years Lived With Disability Attributed to COVID‐19, 2020–2021, Across 920 Locations

Med Research, EarlyView.
The COVID‐related measure known as “years lived with disability” (YLDs) in 2021 may serve as an early warning sign of potential long COVID burden in the years that follow. This nonfatal health measure revealed that, from a global perspective, women (especially those over age 20) and adults aged 20–54 may have borne a higher share of COVID's long ...
Dan Shan, Wenyi Jin, Fei Li, Chengliang Yang, You Zeng, Ruiling Xie, Qingjia Zeng, Yi Chen, Haowei Wang, Christine Linehan, Claire Chenwen Zhong, Qiaoyu Shao, Xiaozhu Liu, Wen Chen, Tongrui Shang, Dong Wang, Yuanyuan Wan, Ningning Wu, Minzhi Lv, Zhihui Li, Yue Qiu, Wei Wang, Xian Shao, Ruhai Bai, Lili Zheng, Baozhen Huang, Weize Xu, Changchang Li, Zimeng Wu, Guangyao Cai, Yuanyuan Chen, Ying Wang, Shuang Hu, Liang Zhang, Lerong Chen, Jianhua Huang, Scott J. Tebbutt, Ting Luo, Queran Lin, Salman Rawaf, Azeem Majeed, for the GBD 2021 Long COVID Impact and Inequality Collaborators   +41 more
wiley   +1 more source

Impact of different hypertensive disorders of pregnancy on cardiovascular disease risk and all-cause mortality in women with type 1 diabetes. [PDF]

Cardiovasc Diabetol
Rimpeläinen K, Jansson Sigfrids F, Gordin D, Klemetti MM, Harjutsalo V, Groop PH, Thorn LM, FinnDiane Study Group.   +7 more
europepmc   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Pregnancy complications and cardiovascular disease death: 50-year follow-up of the Child Health and Development Studies pregnancy cohort.

Circulation, 2015
P. Cirillo, B. Cohn
semanticscholar   +1 more source

A new prediction diagnosis model of incomplete Kawasaki disease based on data mining with big data

Pediatric Discovery, EarlyView.
In this study, based on a medical big data information mining approach, we mined the independent risk factors for incomplete Kawasaki disease prediction by comparing incomplete Kawasaki disease with related febrile illnesses and constructed an auxiliary diagnostic model used to predict incomplete Kawasaki disease.
Zhen Yang, Bo Pan, Jia Liu, Haolin Wang, Jie Tian   +4 more
wiley   +1 more source

<i>A heart that cares</i>: Providing utmost care to mothers with multiple pregnancies. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Cordero DA.
europepmc   +1 more source

Future cardiovascular risk prediction in women with pregnancy complications: the HUNT is on

European Heart Journal, 2019
Denise Hilfiker-Kleiner, Tobias Koenig
openaire   +3 more sources

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

Pediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao, Zhongying Yang, Yu He, Jianhua Wei, Luo Ren, Enmei Liu, Na Zang   +6 more
wiley   +1 more source