Oxidative stress, protein glycation and nutrition – interactions relevant to health and disease throughout the lifecycle [PDF]
Protein glycation has been studied for over a century now and plays an important role in disease pathogenesis throughout the lifecycle. Strongly related to diabetic complications, glycation of Hb has become the gold standard method for diabetes diagnosis
American Diabetes+17 more
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Abstract Objective To evaluate the 1‐year efficacy of subcutaneous immunotherapy (SCIT) in treating dust mite‐induced allergic rhinitis (AR) and establish objective biomarkers for efficacy monitoring. Methods Fifty‐nine AR patients underwent 1‐year SCIT. Subjective symptoms were assessed via total nasal symptom score (TNSS), combined symptom/medication
Jingwen Wang+4 more
wiley +1 more source
The oral microbiome and adverse pregnancy outcomes. [PDF]
Significant evidence supports an association between periodontal pathogenic bacteria and preterm birth and preeclampsia. The virulence properties assigned to specific oral pathogenic bacteria, for example, Fusobacterium nucleatum, Porphyromonas ...
Angolkar, Mubashir+5 more
core +3 more sources
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli+17 more
wiley +1 more source
Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]
Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A.+9 more
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BUN‐to‐ALB ratio as an effective predictor of 30 day mortality in ADHF patients in eastern China
Abstract Aims The blood urea nitrogen‐to‐albumin ratio (BAR) is considered a potential indicator for assessing the poor prognosis of heart failure (HF). However, its prognostic value for Chinese patients with acute decompensated HF (ADHF) remains unclear.
Xin Huang+8 more
wiley +1 more source
TESTING PATTERNS FOR SYPHILIS AND OTHER SEXUALLY TRANSMITTED INFECTIONS IN PREGNANT WOMEN PRESENTING TO EMERGENCY DEPARTMENTS [PDF]
Following an initial decrease in the incidence of congenital syphilis from 2008-2012, the rate of congenital syphilis rose by 38% across the United States between 2012-2014 (2).
SHOYOMBO, IFEOLUWA
core +1 more source
Obstetric and long-term kidney outcomes in renal transplant recipients: a 40 year single-centre study [PDF]
Female renal transplant recipients of childbearing age may ask what the outcomes are for pregnancy and whether pregnancy will affect graft function. We analyzed obstetric and transplant outcomes among renal transplant recipients in our center who have ...
Brennand, Janet E.+6 more
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Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial
Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in patients with ...
Zhuoshan Huang+18 more
wiley +1 more source
A prospective study of implantation, maternal cardiovascular function and pregnancy outcome [PDF]
Events at embryonic implantation play a key role in the establishment of successful pregnancy. Not only is delayed implantation associated with an increased incidence of early pregnancy loss, but may also be associated with impaired trophoblastic ...
Mahendru, Amita
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