Results 131 to 140 of about 61,039 (242)

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

Severe Acute Respiratory Syndrome by COVID-19 in pregnant and postpartum women

Revista Brasileira de Saúde Materno Infantil
Objectives: to evaluate the morbidity and mortality profile and factors associated with death due to severe acute respiratory syndrome (SARS) by COVID-19 in pregnant and postpartum women.
Ana Paula Nogueira Godoi, Gilcelia Correia Santos Bernardes, Nivea Aparecida de Almeida, Saulo Nascimento de Melo, Vinícius Silva Belo, Leilismara Sousa Nogueira, Melina de Barros Pinheiro   +6 more
doaj   +2 more sources

Wireless blood pressure sensor implantation in sheep: A detailed technique

Animal Models and Experimental Medicine, EarlyView.
Twelve adult sheep underwent wireless blood pressure sensor implantation. The procedure lasted an average of 36 min, with mean systolic and diastolic blood pressures of 93 ± 6 and 65 ± 5 mmHg, respectively. This rapid, minimally invasive protocol is a powerful platform for cardiovascular device development.
David Santer, Paul Ecker, Judith Radloff, Katharina Heissl, Smruti Mirchandani, Sabine Leitner, Bruno Mora, Martin Czerny, Roman Gottardi, Michael Moore, Bruno K. Podesser   +10 more
wiley   +1 more source

Gestantes con antígeno de superficie positivo: resultado de su pesquisaje en 5 837 casos

Revista Cubana de Higiene y Epidemiología
Se realiza un estudio observacional, analítico, con un modelo de diseño del tipo casos y controles; en un total de 5 837 gestantes, pesquisadas en los municipios Guanabacoa y Regla desde el 1 de junio de 1990 hasta el 1 de junio de 1994. Se detectaron 20
Rodolfo Fernández Milián, Gil Vicente Sarmiento Brooks, Luis Fernández Machín, Carmen Córdova Medina   +3 more
doaj  

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Antibacterial therapy in preterm labor and prelabor rupture of fetal membranes

RUDN Journal of Medicine, 2011
Preterm labor and prelabor rupture of fetal membranes is one of the most challenging and contradictory problems of obstetrics. From one hand, prolongation of preterm pregnancy increases the gestational age of the fetus.
K S Podtetenev, A A Orazmuradov, E A Shishkin, A Y Pasternak, A A Lukaev, Y V Zykov   +5 more
doaj  

Reviewing disease burden among rural Indian women [PDF]

, 2004
The disease burden of rural Indian women is reviewed by utilizing the data from the 'Survey of Causes of Death (rural)' annual reports of Registrar General of India supplemented with National family health survey (NFHS-II).
Agnihotram V, Dr. Ramanakumar
core  

Start With a Girl: A New Agenda for Global Health [PDF]

, 2009
Examines how social factors shape the health issues adolescent girls face in developing countries. Calls for a health agenda for girls, including focused HIV prevention and maternal health advocacy; elimination of child marriage; and secondary ...
Miriam Temin, Ruth Levine
core  

Mpox (Monkeypox) in Pregnancy Updates

Health Science Reports
Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates.
Yeshey Dorjey, Deep Kiran Chhetri
doaj   +1 more source

Over the edge: Empirical evidence for the cliff‐edge model of obstetric selection

The Anatomical Record, EarlyView.
Abstract The cliff‐edge model of obstetric selection maintains that larger neonates and smaller birth canals confer a positive selective advantage until labor becomes obstructed and vaginal delivery is no longer possible, eliciting an abrupt reduction in fitness.
Laura M. Watson, Pierre Frémondière, Kaspar Staub, Philipp Mitteroecker, Barbara Fischer, Martin Haeusler, Nicole M. Webb   +6 more
wiley   +1 more source